Title |
New insights into the role and mechanism of macrophage migration inhibitory factor in steroid-resistant patients with systemic lupus erythematosus
|
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Published in |
Arthritis Research & Therapy, May 2012
|
DOI | 10.1186/ar3828 |
Pubmed ID | |
Authors |
Fang-Fang Wang, Li-An Zhu, Yu-Qiong Zou, Hui Zheng, Alisa Wilson, Cheng-De Yang, Nan Shen, Daniel J Wallace, Michael H Weisman, Shun-Le Chen, Liang-Jing Lu |
Abstract |
Glucocorticoid (GC) therapy remains important in improving the prognosis of patients with systemic lupus erythematosus (SLE). However, some patients do not achieve an effective response with GC treatment, creating an obstacle to the remission of SLE. Identification of the underlying mechanisms responsible for steroid resistance can be significant. Macrophage migration inhibitory factor (MIF) arouses our interest because of its reciprocal relationship with GCs. In the present study, we investigated for the first time whether MIF correlated with steroid resistance in SLE and explored potential mechanisms of action. |
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United Kingdom | 1 | 100% |
Demographic breakdown
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
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Unknown | 29 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 23% |
Researcher | 5 | 17% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 4 | 13% |
Unknown | 7 | 23% |
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Immunology and Microbiology | 1 | 3% |
Other | 1 | 3% |
Unknown | 8 | 27% |