@EMPoisonPharmD That said, I will disagree that there has not been human data. The proof-of-concept that fomepizole reduces oxidative metabolism in APAP has been demonstrated prospectively and impressively in (safely) poisoned human volunteers. https://
RT @ebtapper: Acetaminophen causes liver damage when it is oxidized. NAC is a great antidote But is there a way to stop the oxidation?…
RT @SteveCurryMD: Animal data also demonstrate 4MP's prevention of cJNK activation downstream from NAPQI formation & prevention of hepaotox…
Animal data also demonstrate 4MP's prevention of cJNK activation downstream from NAPQI formation & prevention of hepaotoxicity when 4MP is given after oxidative metabolism complete. https://t.co/l7NyUloV7e
RT @ebtapper: Acetaminophen causes liver damage when it is oxidized. NAC is a great antidote But is there a way to stop the oxidation?…
RT @ebtapper: Acetaminophen causes liver damage when it is oxidized. NAC is a great antidote But is there a way to stop the oxidation?…
Acetaminophen causes liver damage when it is oxidized. NAC is a great antidote But is there a way to stop the oxidation? Looks that way! By Fomepizole! Check out this study in healthy volunteers given a bunch of tylenol https://t.co/4YTEyu8WiD #tox #li
Articles: The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers. https://t.co/vXf492Wbba Fomepizole as an Adjunctive Treatment in Severe Acetaminophen Toxicity. https://t.co/3ZGfSaF2kD 2/3
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
@MedToxFellowshp @ToxAndHound
Read the complete 4-MP for APAP study here: https://t.co/eLPg4QapFy
RT @JMT_tweets: The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers | OnlineFirst at JMT @acmt @…
@EMpharmD_Hays @pharmdKP
RT @JMT_tweets: The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers | OnlineFirst at JMT @acmt @…
The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers | OnlineFirst at JMT @acmt @SpringerTox https://t.co/aqUprq6Bzp
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
The trial which resulted in my profile picture. Fomepizole decreases excretion of oxidative metabolites of APAP.
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
@UAzMedPhxChair @rbaselt
RT @SteveCurryMD: Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.c…
Our new paper on inhibition of oxidative metabolism of acetaminophen by 4-methylpyrazole in human volunteers. https://t.co/G0F12N87p0 @MedToxFellowshp @ToxAndHound https://t.co/DINTu2hsHY