IFN-γ down-regulates the PD-1 expression and assist nivolumab in PD-1-blockade effect on CD8+ T-lymphocytes in pancreatic cancer

RT @keisuke4713: PD-1⬆️→T細胞受容体を介したeffector活性を特異的妨害、T細胞の機能不全や疲労 IFN-γがCD8+T細胞上PD-1発現⬇️→膵癌でnivolumabの抗腫瘍細胞毒性⬆️ https://t.co/XAhUbUcS70 ＊やはり、意…

PD-1⬆️→T細胞受容体を介したeffector活性を特異的妨害、T細胞の機能不全や疲労 IFN-γがCD8+T細胞上PD-1発現⬇️→膵癌でnivolumabの抗腫瘍細胞毒性⬆️ https://t.co/XAhUbUcS70 ＊やはり、意図的に仕掛けている？🤔 ⾮修飾OVA-LNP💉🐭はPD-1+CD4+T細胞⬆️ m1Ψ修飾100％OVA-LNP💉🐭は PD-1+CD8+T細胞⬆️⬆️ https://t.co/uKSd7qLI7Y

IFN-γ down-regulates the PD-1 expression and assist nivolumab in PD-1-blockade effect on CD8+ T-lymphocytes in pancreatic cancer. https://t.co/aNlXVLR147

RT @StojdlLab: Treating mice with IFN-gamma downregulates PD-1 expression on T cells to enhance nivolumab activity & promote T cell prolife…

Treating mice with IFN-gamma downregulates PD-1 expression on T cells to enhance nivolumab activity & promote T cell proliferation, cytokine secretion & cytotoxicity during #cancer #immunotherapy: https://t.co/YQ8A82fH85 #OA @BioMedCentral @ZJU_off