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A genomewide scan of male sexual orientation

Overview of attention for article published in Human Genetics, January 2005
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#7 of 2,562)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
5 news outlets
blogs
6 blogs
twitter
4 tweeters
wikipedia
3 Wikipedia pages
googleplus
2 Google+ users
video
3 video uploaders

Citations

dimensions_citation
115 Dimensions

Readers on

mendeley
210 Mendeley
citeulike
1 CiteULike
Title
A genomewide scan of male sexual orientation
Published in
Human Genetics, January 2005
DOI 10.1007/s00439-004-1241-4
Pubmed ID
Authors

Brian S. Mustanski, Michael G. DuPree, Caroline M. Nievergelt, Sven Bocklandt, Nicholas J. Schork, Dean H. Hamer

Abstract

This is the first report of a full genome scan of sexual orientation in men. A sample of 456 individuals from 146 families with two or more gay brothers was genotyped with 403 microsatellite markers at 10-cM intervals. Given that previously reported evidence of maternal loading of transmission of sexual orientation could indicate epigenetic factors acting on autosomal genes, maximum likelihood estimations (mlod) scores were calculated separated for maternal, paternal, and combined transmission. The highest mlod score was 3.45 at a position near D7S798 in 7q36 with approximately equivalent maternal and paternal contributions. The second highest mlod score of 1.96 was located near D8S505 in 8p12, again with equal maternal and paternal contributions. A maternal origin effect was found near marker D10S217 in 10q26, with a mlod score of 1.81 for maternal meioses and no paternal contribution. We did not find linkage to Xq28 in the full sample, but given the previously reported evidence of linkage in this region, we conducted supplemental analyses to clarify these findings. First, we re-analyzed our previously reported data and found a mlod of 6.47. We then re-analyzed our current data, after limiting the sample to those families previously reported, and found a mlod of 1.99. These Xq28 findings are discussed in detail. The results of this first genome screen for normal variation in the behavioral trait of sexual orientation in males should encourage efforts to replicate these findings in new samples with denser linkage maps in the suggested regions.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 210 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 2%
United States 4 2%
China 2 <1%
France 1 <1%
Mexico 1 <1%
Sweden 1 <1%
Colombia 1 <1%
Canada 1 <1%
Unknown 195 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 50 24%
Student > Ph. D. Student 37 18%
Researcher 29 14%
Student > Master 29 14%
Professor 15 7%
Other 50 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 30%
Psychology 42 20%
Medicine and Dentistry 26 12%
Social Sciences 22 10%
Biochemistry, Genetics and Molecular Biology 17 8%
Other 41 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 92. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2019.
All research outputs
#178,834
of 13,606,884 outputs
Outputs from Human Genetics
#7
of 2,562 outputs
Outputs of similar age
#1,075
of 120,818 outputs
Outputs of similar age from Human Genetics
#1
of 26 outputs
Altmetric has tracked 13,606,884 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,562 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,818 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.