@R_H_Ebright @AndrewButchart1 @acritschristoph @stuartjdneil @Rossana38510044 @NaomiOreskes @K_G_Andersen Interestingly, this paper that says direct demonstration of cleavage at RRARSVAS in human ENaC was not published until Nov 2019 (and not by UNC)! It's
@stuartjdneil @PaulBieniasz @Rossana38510044 @NaomiOreskes UNC work on RKRR (and other cleavage sites): https://t.co/2Gyth4gKAe Human γ RKRR: https://t.co/LB8ZhLv9tR (cleavage after 138) Useful reference: https://t.co/RQ4OkIX39k (but needs care in data int
RT @babarlelephant: @R_H_Ebright @ydeigin @acritschristoph For clarity, mouse ENaC is better studied than human, and its cleavage differ, b…
@babarlelephant @R_H_Ebright @ydeigin @acritschristoph @babar Is it right that before Nov 2019, the cleavage was shown in the mouse channel with RSTR|D, and only in Nov 2019 was it published for the human channel with RRAR|S? https://t.co/Y2IyiS9n2U: "pote
@R_H_Ebright @ydeigin @acritschristoph For clarity, mouse ENaC is better studied than human, and its cleavage differ, but there is at least one article https://t.co/ig4YGjCIE5 showing that human αENaC is cleaved by furin at our motif similar to SARS-CoV-2
The epithelial Na+ channel α- and γ-subunits are cleaved at predicted furin-cleavage sites, glycosylated and membrane associated in human kidney. #EVs https://t.co/lxFD4rAqaz
The epithelial Na+ channel α- and γ-subunits are cleaved at predicted furin-cleavage sites, glycosylated and membrane associated in human kidney. https://t.co/C34dOvqAWK