@BiotechMongoose @dkjhaunc We've been pretty loose with our nomenclature, for sure. What we typically call essential genes in mammalian KO screens are those that cause a sufficient fitness defect that they'd be rapidly outcompeted by WT cells. E.g. Fig 1 h
1,412 followers
2,826 followers
Latest from the Moffat lab: #BAGEL- fast & accurate tool for finding essential genes from pooled library screens https://t.co/B98YbSqBTg
176 followers
BAGEL: a computational framework for identifying essential genes from pooled library screens https://t.co/F5tOkWGCVa #bmcbioinformatics
166 followers
BAGEL: a computational framework for identifying essential genes from pooled library screens: The adaptation o... https://t.co/fAHqjAbwvC
2,938 followers
BAGEL: a computational framework for identifying essential genes from pooled library screens: The adaptation… https://t.co/LLvzMb1bJz #BMC
261 followers
BMC: BAGEL: a computational framework for identifying essential genes from pooled library screens: The adaptat... https://t.co/zBjbjOHqUG