Mechanisms of Resistance to Monoclonal Antibodies (mAbs) in Lymphoid Malignancies

Overview of attention for article published in Current Hematologic Malignancy Reports, September 2019

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In the top 25% of all research outputs scored by Altmetric
Among the highest-scoring outputs from this source (#34 of 434)
High Attention Score compared to outputs of the same age (84th percentile)
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综述 | 单克隆抗体的耐药机制

CN-Healthcare, 28 Apr 2022

前言在过去的20年里，使用单克隆抗体(mAb)的被动免疫治疗已经彻底改变了癌症的治疗，特别是恶性血液病。虽然单克隆抗体的使用改善了预后，但在大多数情况下，耐药性的产生是不可避免的。最近的研究结果确定了耐药性的机制，包括改变抗原表达或结合，受损的补体介导的细…