RT @osvaldoics: We couldn’t replicate MNase digestion as described here: Quantitative MNase-seq accurately maps nucleosome occupancy levels…
We couldn’t replicate MNase digestion as described here: Quantitative MNase-seq accurately maps nucleosome occupancy levels | @GenomeBiology Someone with a replicable protocol? ✨🙏🏽 https://t.co/1fYhUcFwfO
RT @interactivefly: Quantitative MNase-seq accurately maps nucleosome occupancy levels in #Drosophila https://t.co/y2vwNpAwch
Quantitative MNase-seq accurately maps nucleosome occupancy levels in #Drosophila https://t.co/y2vwNpAwch
Quantitative MNase-seq accurately maps nucleosome occupancy levels https://t.co/KROqjaGtHf
RT @aemonten: "Here, we introduce a theoretical framework for predicting nucleosome occupancies & an experimental protocol that provides ac…
New work out from the Henikoff group in @BioMedCentral provides a quantitative model for determining nucleosome occupancy by MNase-seq that is unaffected by MNase sequence bias of and level of digestion. #chromatin #epigenetics https://t.co/6uN6RnuFIn
Quantitative MNase-seq accurately maps nucleosome occupancy levels #genome https://t.co/NRBI5K1T4C
"Here, we introduce a theoretical framework for predicting nucleosome occupancies & an experimental protocol that provides accurate occupancy levels over an MNase digestion time course." Quantitative MNase-seq accurately maps nucleosome occupancy lev
RT @Nucleosome_Bot: Quantitative MNase-seq accurately maps nucleosome occupancy levels. https://t.co/gh8UMa75nQ
Quantitative MNase-seq accurately maps nucleosome occupancy levels. https://t.co/gh8UMa75nQ
Quantitative MNase-seq accurately maps nucleosome occupancy levels. https://t.co/sR13Y6WObh
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @GenomeBiology: New method from @rchereji, Bryson & Henikoff for analyzing MNase-seq data to determine nucleosome occupancy. Nucleosomes…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @rchereji: If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends…
RT @GenomeBiology: New method from @rchereji, Bryson & Henikoff for analyzing MNase-seq data to determine nucleosome occupancy. Nucleosomes…
If you ever wondered why the results of traditional MNase-seq experiments were so variable (i.e. nucleosome occupancy depends on the level of digestion), here is the explanation. We developed a new quantitative method to analyze MNase-seq data, qMNase-seq:
Bookmarking,
New method from @rchereji, Bryson & Henikoff for analyzing MNase-seq data to determine nucleosome occupancy. Nucleosomes are sensitive to the degeree of digestion: light digestion only releases the most accessible ones. This method takes that into acco