RT @aemonten: "The chained structure of gene enhancers reveals that the primary, critical enhancer is distal, commonly located further away…
"The chained structure of gene enhancers reveals that the primary, critical enhancer is distal, commonly located further away than other enhancers." The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance h
Very interesting! Not all enhancers are created equal!!
RT @tangming2005: The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance https://t.co/bEs…
RT @tangming2005: The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance https://t.co/bEs…
The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance. https://t.co/Uk1NOzcoLI
Just when you thought molecular biology couldn’t get any more complicated...
RT @tangming2005: The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance https://t.co/bEs…
The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance https://t.co/bEscmNEhXc
The 1st enhancer in a chain of enhancers safeguards subsequent enhancer-promoter contacts from a distance. Relative to others in a chain, first enhancer that forms most stable chromatin loop with target promoter will establish a baseline in its regulation
Song, Sharan and Ovcharenko map chains between enhancers and target promoters. The first enhancer in a chain is at a larger distance from the promoter than the second enhancer is. The first enhancer is critical in determining tissue-specific expression htt