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Modified Natural Clinoptilolite Detoxifies Small Mammal’s Organism Loaded with Lead I. Lead Disposition and Kinetic Model for Lead Bioaccumulation

Overview of attention for article published in Biological Trace Element Research, December 2011
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  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

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4 tweeters
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1 Facebook page

Citations

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14 Dimensions

Readers on

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10 Mendeley
Title
Modified Natural Clinoptilolite Detoxifies Small Mammal’s Organism Loaded with Lead I. Lead Disposition and Kinetic Model for Lead Bioaccumulation
Published in
Biological Trace Element Research, December 2011
DOI 10.1007/s12011-011-9278-4
Pubmed ID
Authors

Michaela Beltcheva, Roumiana Metcheva, Nikolay Popov, Svetla E. Teodorova, J. Antonio Heredia-Rojas, Abraham O. Rodríguez-de la Fuente, Laura E. Rodríguez-Flores, Margarita Topashka-Ancheva

Abstract

Zeolites, especially clinoptilolites, have wide application in removing heavy metals from different solutions and wastewater. The detoxification capacity of the clinoptilolite sorbent KLS-10-MA, a modified natural Bulgarian zeolite, applied as a food supplement in conditions of an ecotoxicological experiment with conventional food and lead was demonstrated for the first time. Laboratory mice, inbred imprinting control region strain, were used in a 90-day ecotoxicological experiment. Animals were divided into four experimental groups. Lead bioaccumulations in exposed and non-supplemented/supplemented with KLS-10-MA animals were compared. As additional control, healthy animals non-exposed to Pb were fed with conventional forage mixed with 12.5% KLS-10-MA. The dietary inclusion of the sorbent reduced Pb concentrations in exposed and supplemented mice by 84%, 89%, 91%, 77%, and 88% in carcass, liver, kidneys, bones, and feces, respectively. A mathematical model was proposed to outline the common trends of bone Pb bioaccumulation in exposed and non-supplemented/supplemented animals. Characteristic parameters of the kinetics of Pb concentrations were determined. Based on the model, the coefficient of absorption of Pb by gastrointestinal mucosa in the supplemented mice was found-η = 3.53% (versus η = 15% in non-supplemented ones). The present study clearly indicates that there is a realistic perspective to create a new drug based on modified natural clinoptilolites in cases of chronic heavy metal intoxication, without negatively affecting the environment.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 10%
Unknown 9 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 40%
Student > Bachelor 1 10%
Student > Doctoral Student 1 10%
Other 1 10%
Professor > Associate Professor 1 10%
Other 0 0%
Unknown 2 20%
Readers by discipline Count As %
Environmental Science 1 10%
Biochemistry, Genetics and Molecular Biology 1 10%
Nursing and Health Professions 1 10%
Economics, Econometrics and Finance 1 10%
Social Sciences 1 10%
Other 2 20%
Unknown 3 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2019.
All research outputs
#3,649,177
of 13,989,129 outputs
Outputs from Biological Trace Element Research
#184
of 1,310 outputs
Outputs of similar age
#29,359
of 121,753 outputs
Outputs of similar age from Biological Trace Element Research
#3
of 13 outputs
Altmetric has tracked 13,989,129 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,310 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,753 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.