Title |
Energy metabolic dysfunction as a carcinogenic factor in cancer cells
|
---|---|
Published in |
Clinical and Translational Medicine, April 2016
|
DOI | 10.1186/s40169-016-0094-5 |
Pubmed ID | |
Authors |
Yongyan Sun, Zhenhua Shi, Huiyong Lian, Peng Cai |
Abstract |
Cancer, as a leading cause of death, has attracted enormous public attention. Reprogramming of cellular energy metabolism is deemed to be one of the principal hallmarks of cancer. In this article, we reviewed the mutual relationships among environmental pollution factors, energy metabolic dysfunction, and various cancers. We found that most environmental pollution factors could induce cancers mainly by disturbing the energy metabolism. By triggering microenvironment alteration, energy metabolic dysfunction can be treated as a factor in carcinogenesis. Thus, we put forward that energy metabolism might be as a key point for studying carcinogenesis and tumor development to propose new methods for cancer prevention and therapy. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Russia | 1 | 3% |
Denmark | 1 | 3% |
Unknown | 29 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 6 | 19% |
Student > Ph. D. Student | 6 | 19% |
Student > Master | 5 | 16% |
Student > Doctoral Student | 3 | 10% |
Professor > Associate Professor | 2 | 6% |
Other | 4 | 13% |
Unknown | 5 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 23% |
Medicine and Dentistry | 6 | 19% |
Biochemistry, Genetics and Molecular Biology | 5 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Nursing and Health Professions | 1 | 3% |
Other | 3 | 10% |
Unknown | 7 | 23% |