5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-xL

Overview of attention for article published in Molecular and Cellular Biochemistry, July 2019

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interesting... re Bcl-xL & KRAS Reversal of Mutant KRAS-mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer 2014 research from K.Okamoto, A. Zaanan, H. Kawakami, S. Huang & F. A. Sinicrope

01 Aug 2019

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5-FU preferably induces apoptosis in BRAFV600E #colorectacancer cells via downregulation of Bcl-xL "..inhibition of Bcl-xL might present an alternative strategy to enhance the therapeutic efficacy of 5-FU in colorectal cancer patients with #BRAF mutation."

01 Aug 2019

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