@The2Margarets @alitlstrawberry @mdbtvh Here’s a summary of the research. I’m sure the account selling you coenzyme Q will send a link to the clinical trials showing the expensive product protects against tendon rupture. (Translated: if they don’t it’s li
@edouriez @FLAHAULT @FZores https://t.co/PUw1bHZL43 Important de noter que les études de cohortes sous estiment l'effet en ne considérant en général qu'une période de risque de 30 jours et du coup contamination du groupe contrôle, en + biais de selection e
@doc1111111 @Cernovich https://t.co/gxc1Vvm1kq Important to note also literature grossly underestimates tendinopathy risks by using cohort studies with short 30 to 60 days risk period despite the well documented delayed (month or even years) onset tendinop
@BJegorovic @drtimothyli https://t.co/gxc1Vvm1kq You could warned them about how literature underestimates tendinopathy risks by using cohort studies with short 30 to 60 days risk period despite the well documented delayed onset tendinopathies and contamin
@SFPT_fr @Nicematinnyc @Reseau_CRPV https://t.co/PUw1bHZL43 ..sous estimés par la littérature qui persiste à ne considérer que les effets à court terme avec études de cohortes avec des périodes de risque très courtes (30 jours le plus souvent) alors que le
RT @phellinckx: @colchimaxx https://t.co/PUw1bHZL43 ...les risques tendineux en s'obstinant à se baser sur des études de cohortes avec des…
@colchimaxx https://t.co/PUw1bHZL43 ...les risques tendineux en s'obstinant à se baser sur des études de cohortes avec des périodes de risque de 30 jours (alors que les effets décalés sont documentés depuis des décennies) et prétendant ignorer que ces effe
RT @phellinckx: @Asclepios_YT .https://t.co/PUw1bI0iTB ..Je suis attristé de constater le manque d'information des médecins concernant les…
RT @phellinckx: @Asclepios_YT .https://t.co/PUw1bI0iTB ..Je suis attristé de constater le manque d'information des médecins concernant les…
@Asclepios_YT .https://t.co/PUw1bI0iTB ..Je suis attristé de constater le manque d'information des médecins concernant les EI des fluoroquinolones et l'extrême pauvreté (pour rester poli..) de la littérature avec des études de cohortes qui sous estiment gr
@CaitlynMooneyMD @Drjasonmatuszak @DuchessSexpert https://t.co/gxc1Vvmz9Y But despite the well documented delayed onset tendinopathies, prescribers persist to hide behind cohort studies using ridiculously short 30 to 60 days risk period, contaminated contr
@Retlouping @envivoPT @DrPeteMalliaras https://t.co/gxc1Vvm1kq ...or even years later have been well documented for nearly 30 years. But prescribers are hiding behind cohort studies using r30 day risk period, contaminated control group, crippled with confo
@erintbird @PBajicMD https://t.co/0DkTRB7nM6 "Consequently, the use of fluoroquinolones, even if months to years ago, should always be considered as a cause" But cohort studies stubbornly persist to consider... 30 days risk period. Cognitive dissonance, hi
@IlindelatorreMD https://t.co/iiv0mzd80Y Also important to underline musculoskeletal adverse effects from fluoroquinolones are grossly underestimate by cohort studies only considering very short risk period excluding delayed onset. Not to mention selectio
@HadrienVac https://t.co/gEmrNCvmt8 Il important de souligner que la littérature sous-estime grossièrement le risque de tendinopathie causée par la fluoroquinolone en s'appuyant obstinément sur des études de cohorte utilisant une période de risque ridicule
@fereshtehjahan1 @vijayiyer312 https://t.co/RB6dMnwUm2 Also important to underline literature is grossly underestimating risk of tendinopathy caused by fluoroquinolone stubbornly relying on cohort studies using ridiculously short risk period (usually 30 da
@j0nnyb0y1 @kalamityjack @ModelAyshaMirza @Blitz_y https://t.co/hIiLzIAQiN Fluoroquinolone induced tendinopathy are grossly underestimated based on cohort studies using ridiculously short risk period (mostly 30 days...) to claim they are "very rare" when t
@tummalapallive4 @LinkedIn https://t.co/hIiLzIjfrf Fluoroquinolone induced tendinopathy delayed by several month or years are well documented since decades but cohort studies are stubbornly using 30 days risk period to claim they are "very rare"
RT @phellinckx: @iceman_ex @load_dependent https://t.co/GqqBUbeg3e Meta-analysis, la crème de la crème when it comes to EBM But garbage in,…
@PGtzsche1 https://t.co/gxc1Vvm1kq Even worse with fluoroquinolones where focus is on gaslighting victims of AE, claiming it is "very rare" based on very poor literature using ridiculously short risk period (generally 30 days) despite that delayed onset AE
RT @phellinckx: @gurdeep_dulay https://t.co/gxc1Vvm1kq Unfortunately exactly the opposite happening for 30 years. Focus is on gaslighting o…
@gurdeep_dulay https://t.co/gxc1Vvm1kq Unfortunately exactly the opposite happening for 30 years. Focus is on gaslighting of patients and claiming that the risks are very low hiding behind ludicrous cohort studies using 30 days risk period despite delayed
@IDstewardship @TomSchmidt30 https://t.co/iiv0mzd80Y Taking into account AE which can be delayed for months or years it is clearly ludicrous to continue claiming they are "very rare" based on cohort studies with a 30 days risk period. Not to mention select
@argonauticalart @soultakerslewds https://t.co/BuW2pz9U5D Unfortunately it is not very rare. Risks are grossly underestimated by cohort studies considering only damages diagnosed within 30 days after stopping the treatment when they can occur months or yea
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@SillyPutty78 @briebriejoy "...and can result in surgery, but they may also occur years after fluoroquinolone use" But doctors still claim that tendinopathy resulting from fluoroquinolone use is "very rare" based on cohort studies with a ridiculously shor
@DrImranSheikh https://t.co/Czix0UhoZA It is also important to underline that adverse effects from fluoroquinolones are grossly underestimated as cohort studies are mostly considering a risk period of 30 days despite the well documented delayed onset up to
@figonoir @1APariente @XavierBerardMD @charles_cazanav https://t.co/A2EysJDPn7 Il est d'ailleurs remarquable que les tendinopathies suite à une prescription de fluoroquinolone sont encore considérés comme "rares" ...en se basant sur des études de cohortes
e.g. tendon rupture associated with fluoroquinolones apparently happens EVEN AFTER YOU'VE STOPPED? https://t.co/6Wcbn7F1oX
@kaisoapbox https://t.co/920MZj25kx When you write that the % of severe adverse side effects is still low, like <1%, it is not correct as this only concerns the very short term adverse effects. Cohort studies only consider a very short risk period despi
@MartinFierro769 https://t.co/8XIsqHzlfg ..alors que les effets décalés de plusieurs mois voir années sont largement documentés depuis des années, les études de cohortes persiste à considérer des période de risque de 30 jours. Il a fallu 25 ans pour que fi
@IkenoYuki @xjpvY2qxQk2tdoL https://t.co/920MZj25kx But 25 years, all published studies have stubbornly considered ridiculously short risk period despite that delayed onset collagen adverse effects associated with fluoroquinolones have been well demonst
@abcsoka https://t.co/eHgoH6ZzqX Also important to underline adverse effects of fluoroquinolone are grossly underestimated as cohort studies systematically consider ridiculously short risk period despite delayed onset adverse effects have been demonstrated
RT @phellinckx: @CovilleP @Fraslin https://t.co/5k3L4IZTd9 D'autant plus que les risques d'effets indésirables sont plus que probablement l…
RT @phellinckx: @PatrickRataud @GeraldSantucci @LePoint @amalyste https://t.co/eHgoH7haiv Les effets indésirables tendineux des fluoroquino…
@CovilleP @Fraslin https://t.co/5k3L4IZTd9 D'autant plus que les risques d'effets indésirables sont plus que probablement largement sous estimés par les études de cohortes qui se limitent à une période de risque de 30 jours alors que les effets indésirable
@PatrickRataud @GeraldSantucci @LePoint @amalyste https://t.co/eHgoH7haiv Les effets indésirables tendineux des fluoroquinolones décalés dans le temps de plusieurs mois voir plus sont largement documentés depuis des décennies. Mais les études de cohorte c
@corruptimeline @itosettiMD_MBA https://t.co/920MZj25kx But for more than 25 years, prescribers hide behind cohort studies which have stubbornly considered 30 days risk period despite well demonstrated delayed onset tendinopathy associated with fluoroquin
@DocsDel https://t.co/eHgoH7haiv " These musculoskeletal adverse events may be fulminant and can result in surgery, but they may also occur years after fluoroquinolone" But prescribers continue to hide behind cohort studies grossly underestimating occurre
@kikisshh @AreminF https://t.co/b57dqSVeMp It is becoming increasingly difficult for the fluoroquinolones adverse effects deniers to hide behind cohort studies using ridiculously short risk periods of 30 days when delayed onset AE are well recognised since
@DrImranSheikh https://t.co/nQrM0MKFtw .." These musculoskeletal adverse events may be fulminant and can result in surgery, but they may also occur years after fluoroquinolone" But cohort studies with 30 days risk period...seriously? https://t.co/GqqBUbeg
@DrImranSheikh https://t.co/920MZj25kx Important to underline risks are grossly underestimated. For 25 years, all published studies have stubbornly considered ridiculously short risk period despite well demonstrated delayed onset adverse effects associated
@MarkoHosamovic7 https://t.co/920MZj25kx But for more than 25 years, all published studies have stubbornly considered ridiculously short risk period despite well demonstrated delayed onset tendinopathy associated with fluoroquinolone for decades.
@RA_Baldock https://t.co/aJUXwlnWyy Important to underline most ADR risk from fluoroquinolone such as tendinopathy from fluoroquinolone are grossly underestimated with all cohort studies using extremely short risk period despite delayed onset AE well docum
RT @phellinckx: @iceman_ex @load_dependent https://t.co/GqqBUbeg3e Meta-analysis, la crème de la crème when it comes to EBM But garbage in,…
@AZJayDoc https://t.co/aJUXwlnWyy Risk of tendinopathy from fluoroquinolone are grossly underestimated with all cohort studies using extremely short risk period despite delayed onset AE well documented for decades...
@brittany_mking https://t.co/aJUXwlnWyy The risk of tendinopathy from fluoroquinolone are grossly underestimated and monitoring symptoms for 1 month pas treatment is much too short taking into account the delayed onset adverse effects
@DrRitaM_ https://t.co/Di6rebsQt4 ...risk period 90 days, not ridiculously short as usual (typ. 60 days)but still too short to capture delayed onset collagen EA (180 days+) ->risk still underestimated Same applies to all studies regarding tendon damages
@Rx_Ed https://t.co/PUw1bHZL43 Also to be noted that tendon damages are not limited to Achilles. Risks of tendon damages are grossly underestimated by all cohort studies which systematically use a ridiculously short risk period despite well documented del
@dr91s https://t.co/PUw1bHZL43 This is correct, risks are indeed increased by corticosteroid but are also considerable without. Cohort studies systematically underestimate the risk of tendinopathy by using ridiculously short risk period excluding well docu
@Dr_meds https://t.co/PUw1bHZL43 Risks are indeed increased by corticosteroid but are also considerable without. Cohort studies systematically underestimate the risk of tendinopathy by using ridiculously short risk period excluding well documented delayed
@Be_Kinderr @SheanaOchoa https://t.co/PUw1bHZL43 ... the existing literature is extremely poor, persisting to use ridiculously short risk periods despite well documented delayed onset damage which results in grossly underestimating risks
@TylerEngDPT @ORourkeDPT https://t.co/PUw1bHZL43 ..there is not literature on delayed onset and long term collagen damage from fluoroquinolone, there is not real answer to your question. The existing literature is extremely poor, persisting to use ridiculo
RT @phellinckx: @aliciad3 @dr_michaelmarks @Medor_mag https://t.co/PUw1bHZL43 ... underestimates the risks of adverse effects, in particula…
@aliciad3 @dr_michaelmarks @Medor_mag https://t.co/PUw1bHZL43 ... underestimates the risks of adverse effects, in particular MSK, by systematically using a ridiculously short risk period (typically 30 days) despite the abondance of evidence of tendinopathy
@Fred_Chu @blondemedSJW @Rick_Pescatore https://t.co/W5bfmLwmIW Important to underline all cohort studies grossly underestimate tendinopathy risks from fluoroquinolone: Ridiculously short risk period excluding delayed onset. Well documented cases 6 months
Le déni, la colère, la tristesse, l'acceptation ?! Merde mais attend on est en train de faire le deuil de quoi là ??!!!! Des institutions donc de la possibilité de faire un monde commun par les faits établis et donc in fine de la civilisation. https://t.c
RT @phellinckx: @MA_Gagnon @CeciliaRikap @testonife @BlausteinMatias @MGarciaCarrillo https://t.co/PUw1bHZL43 Egalement frappant de constat…
@MA_Gagnon @CeciliaRikap @testonife @BlausteinMatias @MGarciaCarrillo https://t.co/PUw1bHZL43 Egalement frappant de constater le peu de recherche concernant les effets indésirables des médicament, la piètre qualité et la quasi systématique sous estimation
@TrevorThePhysio https://t.co/PUw1bHZL43 ...damage from fluoroquinolone not limited to tendon. Also as for tendinopathy from FQ, all cohort studies persist to grossly underestimate risks by defining extremely short risk period excluding well documented del
@_my_mija https://t.co/W5bfmLeLRo All cohort studies systematically underestimate tendinopathy risks from fluoroquinolone by defining short risk period purposely excluding well documented delayed onset collagen damage. Delayed by 6 months to a year...but r
@stpaulgal49 @OneLegSandpiper https://t.co/W5bfmLeLRo Not so rare in fact all cohort studies grossly underestimate tendinopathy risks from fluoroquinolone by defining short risk period excluding well documented delayed onset. Delayed by 6 months & up t
@drjkahn https://t.co/W5bfmLeLRo Important to underline all cohort studies grossly underestimate tendinopathy risks from fluoroquinolone by defining short risk period excluding well documented delayed onset. 6 months and more delayed onset...but risk perio
@iSteeve @TendonGlasgow https://t.co/W5bfmLeLRo Important to underline all cohort studies grossly underestimate tendinopathy risks from fluoroquinolone by defining short risk period excluding well documented delayed onset. Delayed by 6 months & up to 5
@then_there_was @lon_peralta https://t.co/z28Bg2sFH1 Important to note also that risks of adverse effects from fluoroquinolone are grossly underestimated by studies using very short risk period excluding delayed onset. Could also conclude that smoking is
RT @phellinckx: @HaoYin20 @wise_project https://t.co/W5bfmLeLRo Thanks. Important to underline all cohort studies underestimate risks: Sho…
RT @phellinckx: @HaoYin20 @wise_project https://t.co/W5bfmLeLRo Thanks. Important to underline all cohort studies underestimate risks: Sho…
@HaoYin20 @wise_project https://t.co/W5bfmLeLRo Thanks. Important to underline all cohort studies underestimate risks: Short risk period excluding well documented delayed onset AE Tendinopathy from fluoroquinolones delayed by 6 months & up to 510 days
@Prins_Orange @karringmelkboer https://t.co/PUw1bHZL43 The risk of adverse effects of fluoroquinolone are indeed grossly underestimated by a very poor literature which systematically excludes delayed onset effects
@JGPharmD @mcsassymd https://t.co/PUw1bHZL43 Was prescribed cipro for minor infection, no information about risk. Asked if any counterindication vs sports: None. Took it for 3 days and 2 years later new issues still appearing. Literature systematically un
@EnVoitureSimon2 https://t.co/PUw1bHZL43 Effectivement cohorte très conséquente (faire taire l'excuse habituelle des facteurs confondants) données bien traitées, par contre période de risque, 90j, reste beaucoup trop courte, ignore les effets décalés pourt
RT @phellinckx: @Doctorkhalif1 https://t.co/PUw1bHZL43 Also important to note that all cohort studies without any exception including the l…
@Doctorkhalif1 https://t.co/PUw1bHZL43 Also important to note that all cohort studies without any exception including the last one about AA/AD grossly underestimate the risks of fluoroquinolone by using very short risk period excluding delayed onset EA and
@EdwardLoftus2 @gbsaff @HealioGastro @AnnalsofIM https://t.co/PUw1bHZL43 Important to note that all cohort studies without any exception including the last one about AA/AD grossly underestimate the risks of fluoroquinolone by using very short risk period e
@SimonBreidert https://t.co/PUw1bHZL43 ...the study from Wido uses numbers from the literature which systematically grossly underestimate the risk by using ridiculously short risk period excluding well documented delayed onset adverse effects. Also, recent
@MSKUS_PT_KSA @alaabazaid @ImmortalPT https://t.co/PUw1bHZL43 It is also important to note risks of tendon damages from fluoroquinolone are grossly underestimated by all studies. They all use very short risk period excluding well documented delayed onset a
@SLouangoudom @ASPPHARMD @PCOMGeorgia https://t.co/PUw1bHZL43 ..comes recognising a heavily prescribed treatment seriously harming patients for decades, potential liabilities and resulting widespread denial. Delayed onset (> 6 months) tendons damage wel
RT @phellinckx: @Retlouping @SandyHiltonPT @MyCuppaJo @ForwardMotionPT https://t.co/PUw1bHZL43 Appalling quality of literature when it come…
@EUSmkh https://t.co/PUw1bHZL43 Important to underline rupture is only the tip of iceberg when it comes to adverse effects of fluoroquinolone on tendons. Long term, often irreversible tendinopathy are grossly underestimated by poor literature which systema
RT @phellinckx: @DelhiNfps https://t.co/PUw1bHZL43 Rsks of tendon damages from fluoroquinolone are grossly underestimated as onset can be d…
@DelhiNfps https://t.co/PUw1bHZL43 Rsks of tendon damages from fluoroquinolone are grossly underestimated as onset can be delayed by several month and prescribers persist to hide behind cohort studies with very short risk period despite well documented del
RT @phellinckx: @iceman_ex @load_dependent https://t.co/GqqBUbeg3e Meta-analysis, la crème de la crème when it comes to EBM But garbage in,…
@pash22 @WmHaseltine https://t.co/PUw1bHZL43 Very important point, not emphasised enough up till now (including for treatments ) But phase IV studies are too often very poorly designed such as very short risk period excluding delayed onset even when well d
@Retlouping @SandyHiltonPT @MyCuppaJo @ForwardMotionPT https://t.co/PUw1bHZL43 Appalling quality of literature when it comes to adverse effects does not help patients. Cohort studies grossly underestimating the risks by systematically defining short risk p
@doclamarre @M2bliquis @CoxiTerrienne @conspjustice https://t.co/PUw1bHZL43 Effectivement. L'indigence de la littérature sur le sujet des EA en fait partie. Comme les études de cohorte sur les EA tendineux des fluoroquinolones avec période de risque systém
@AstroTsukino @UntoNuggan @AlexSeanchai https://t.co/PUw1bHZL43 The risks of tendon damages from fluoroquinolone are grossly underestimated as onset can be delayed by several month and prescribers persist to hide behind studies which only consider damages
@sydneyLwhitaker @magg_numm https://t.co/PUw1bHZL43 Also important to underline that adverse effects are idiosyncratic, devastating and life changing for the victims and grossly underestimated by a very poor cohort studies which systematically exclude well
@gikkos1 @joannamoncrieff https://t.co/PUw1bHZL43 Furthermore, at least when it comes to collagen / MSK AE, risks are grossly underestimated by the literature as all cohort studies define a very short risk period which excludes delayed onset despite it is
@GrillsNpastries @PharmaFactz @Khadija_M_Illo https://t.co/PUw1bHZL43 Important to underline that risks are grossly underestimated as all cohort studies define a very short risk period which does not take into account the delayed onset despite it is well d
RT @phellinckx: @DrNancyOlivieri @MarnieWedlake @johndowe49 https://t.co/PUw1bHZL43 Important to underline the appalling quality of the lit…
@DrNancyOlivieri @MarnieWedlake @johndowe49 https://t.co/PUw1bHZL43 Important to underline the appalling quality of the literature when it comes to adverse effects. Defining a risk period which purposely exclude well documented delayed onset AE would lead
RT @phellinckx: @SportPhys https://t.co/PUw1bHZL43 It is important to underline that the risks are grossly underestimated as the onset can…
@SportPhys https://t.co/PUw1bHZL43 It is important to underline that the risks are grossly underestimated as the onset can be delayed by 6 months or more and all cohort studies purposely exclude this by defining ridiculously short risk period. It can also
RT @phellinckx: @PharmaFactz https://t.co/PUw1bHZL43 Also important to underline that Fluoroquinolone risks for tendons are grossly underes…