Key design elements of a pragmatic randomized clinical trial https://t.co/aaz725ZpUH https://t.co/0cUfHRia6Z
What makes pragmatic #RCTs unique? Gamerman et al. propose 4 key elements: "enrolling a real-world population, conducted in a real-world setting, capturing relevant outcomes…, and using an appropriate comparison arm." https://t.co/IUkFUgzMMb
Good news: issues were identified, and there is (slow) progress in addressing them https://t.co/KsSZiEz3ge https://t.co/lURSSNjjJo https://t.co/5cnUD52bU8 https://t.co/pF6a8FzFYy https://t.co/PmhFKmlp5K https://t.co/RHJ9nGqOAI https://t.co/ja6633C9pj http
@RajeevJayadevan •How a data detective exposed suspicious medical trials https://t.co/FPbZSBkVfW •Pragmatic randomized clinical trials: best practices and statistical guidance https://t.co/ja6633C9pj •When are randomised trials unnecessary?Picking signal
RT @DipeshGopal: Things to consider in pragmatic trials: Optimise intervention Match intervention to outcome Bias and blinding Exact trial…
Things to consider in pragmatic trials: Optimise intervention Match intervention to outcome Bias and blinding Exact trial design, e.g. stepped wedge E-trial aspects Ethical approval Useful link 1: https://t.co/9RczoNgqe2 Useful link 2: https://t.co/ljzu