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@IDPharmacometrx @KevinJDownes There is one biomarker available, see https://t.co/tydCwC8Y63
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RT @kellumja: Also, the kidney get's "stressed" with PipTazo. https://t.co/dXiDBkNTjy #C3NJournalClub
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Also, the kidney get's "stressed" with PipTazo. https://t.co/dXiDBkNTjy #C3NJournalClub
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@JASN_News @CCCNPitt @skanegill @priyankapandhi8 @EmLauren122 I’ve cut WAY back on my use of Pip-Tazo. Unclear why it makes the kidney unhappy (we have to say) but both AKI epidemiology (as seen here) and direct evidence of kidney stress with this drug (se
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RT @CCCNPitt: Here is the answer to Tuesday's #AKITrivia question- Vancomycin associated #AKI occurs in up to 43% of patients. This was a t…
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RT @CCCNPitt: Here is the answer to Tuesday's #AKITrivia question- Vancomycin associated #AKI occurs in up to 43% of patients. This was a t…
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RT @CCCNPitt: Here is the answer to Tuesday's #AKITrivia question- Vancomycin associated #AKI occurs in up to 43% of patients. This was a t…
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Here is the answer to Tuesday's #AKITrivia question- Vancomycin associated #AKI occurs in up to 43% of patients. This was a tough question but more information on Pharmacokinetic Urinary Biomarker Data in Critically Ill Patients can be found at https://t.c
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@ICUapothecary @ABsteward @erin_barreto @ScottMicek Other biomarkers of AKI (Nephrocheck TIMP-2+IGFBP7) are higher in Pip-Tazo+Vanco rather than either drug alone, as well as risks of stage 2/3 AKI https://t.co/tydCwC8Y63
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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The combination of vancomycin plus piperacilin-tazobactam increases the cell cycle arrest biomarkers and this combination was higher in patients with #AKI. Also with MAKEs. What do you think? @atselur @DraMarili @croncoIRRIV
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @TimbrookTT: "reafrms that exposure to piperacillin–tazobactam alone increases urinary [TIMP-2]∙[IGFBP7] on day 1, which contributes to…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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RT @CCCNPitt: Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for a…
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Risk of drug-induced nephrotoxicity increases w concomitant drug exposure. A drug combination that has gained attention for additive risk of nephrotoxicity is vancomycin + piperacillin–tazobactam, & some of these findings are published here: https://t.
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Post-exposure to piperacillin–tazobactam & vancomycin in combination, a greater release of #AKI biomarkers in patients who develop AKI occurred than w piperacillin–tazobactam or vancomycin monotherapy; the combo is linked w an increase in adverse outco
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Interesting. The combination seems more nephrotoxic than either individually
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
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RT @CCCNPitt: This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, an…
4,026 followers
This secondary analysis reveals that kidney stress appears on day 1 after exposure to piperacillin–tazobactam, vancomycin, and piperacillin–tazobactam plus vancomycin for patients that progress to stage 2–3 acute kidney injury; read more: https://t.co/Mq1C