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Immunoglobulin G4-related sclerosing cholecystitis presenting as gallbladder cancer: a case report

Overview of attention for article published in Surgical Case Reports, December 2015
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Title
Immunoglobulin G4-related sclerosing cholecystitis presenting as gallbladder cancer: a case report
Published in
Surgical Case Reports, December 2015
DOI 10.1186/s40792-015-0123-4
Pubmed ID
Authors

Kodai Takahashi, Hideto Ito, Toshio Katsube, Ayaka Tsuboi, Masatoshi Hashimoto, Emi Ota, Kazuhito Mita, Hideki Asakawa, Takashi Hayashi, Keiichi Fujino, Sigeru Okamoto

Abstract

Immunoglobulin G4 (IgG4)-related sclerosing disease is a systemic inflammatory syndrome, and an understanding of its characteristics is currently evolving. IgG4-related cholecystitis is a manifestation of IgG4-related sclerosing disease in the gallbladder. This case report describes the clinical, radiographic, and histopathological findings in a young male patient who presented with a synchronous mass in the gallbladder. Serum levels of IgG4 and the IgG4/IgG ratio were normal, and there was no associated autoimmune pancreatitis. Therefore, establishing a preoperative diagnosis of IgG4-related cholecystitis was very difficult, and a differential diagnosis of gallbladder cancer infiltrating the liver was suggested. Postoperative histopathological examination established a diagnosis of IgG4-related cholecystitis definitively. A preoperative diagnosis of IgG4-related cholecystitis, although possible, would have been highly challenging in this case. It is difficult to establish whether surgical intervention is necessary in IgG4-related cholecystitis. Because malignant tumors are frequently suspected with this clinical presentation, surgical intervention should be undertaken only after due deliberation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 2 22%
Professor > Associate Professor 1 11%
Other 1 11%
Student > Doctoral Student 1 11%
Unknown 4 44%
Readers by discipline Count As %
Medicine and Dentistry 5 56%
Unknown 4 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2016.
All research outputs
#20,313,158
of 22,854,458 outputs
Outputs from Surgical Case Reports
#239
of 488 outputs
Outputs of similar age
#324,949
of 387,655 outputs
Outputs of similar age from Surgical Case Reports
#5
of 8 outputs
Altmetric has tracked 22,854,458 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 488 research outputs from this source. They receive a mean Attention Score of 0.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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