| Title |
Prognostic factors in patients with vulvar cancer treated with primary surgery: a single-center experience
|
|---|---|
| Published in |
SpringerPlus, February 2016
|
| DOI | 10.1186/s40064-016-1767-7 |
| Pubmed ID | |
| Authors |
Sayaka Imoto, Morihiko Inamine, Wataru Kudaka, Yutaka Nagai, Akihiko Wakayama, Tomoko Nakamoto, Takuma Ooyama, Yoichi Aoki |
| Abstract |
Vulvar cancer is a relatively rare disease. The aim of this study was to investigate prognostic factors in vulvar squamous cell carcinoma patients treated with primary surgery. Forty cases of vulvar squamous cell carcinoma treated with primary surgery were retrospectively analyzed. Overall survival (OS) and disease-specific survival (DSS) were calculated using the Kaplan-Meier method and prognostic factors were analyzed by multivariate analyses. The median age was 68 years. The FIGO stage distribution was as follows: 18 cases (45.0 %) in stage I, four cases (10.0 %) in stage II, 15 cases (37.5 %) in stage III, and three cases (7.5 %) in stage IV. A radical local excision was performed in 15 patients, and radical vulvectomy in 25 patients, and seven of these patients were treated with postoperative RT. The 5-year DSS rate was 72.6 %, and the 5-year OS rate was 70.3 %. Age and surgical margin ≤5 mm were independent prognostic factors for OS, and positive inguinal LN metastasis and surgical margin ≤5 mm were identified as independent prognostic factors for DSS. Complete radical excision is important regardless of operation mode. Adjuvant treatment should be considered for inguinal LN positive patients. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 19% |
| Student > Ph. D. Student | 3 | 19% |
| Student > Bachelor | 2 | 13% |
| Lecturer > Senior Lecturer | 1 | 6% |
| Professor | 1 | 6% |
| Other | 3 | 19% |
| Unknown | 3 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 50% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
| Chemistry | 1 | 6% |
| Agricultural and Biological Sciences | 1 | 6% |
| Unknown | 5 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2016.
All research outputs
#18,445,779
of 22,854,458 outputs
Outputs from SpringerPlus
#1,259
of 1,849 outputs
Outputs of similar age
#216,483
of 298,013 outputs
Outputs of similar age from SpringerPlus
#102
of 155 outputs
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