| Title |
Emotional enhancement of memory: how norepinephrine enables synaptic plasticity
|
|---|---|
| Published in |
Molecular Brain, January 2010
|
| DOI | 10.1186/1756-6606-3-15 |
| Pubmed ID | |
| Authors |
Keith Tully, Vadim Y Bolshakov |
| Abstract |
Changes in synaptic strength are believed to underlie learning and memory. We explore the idea that norepinephrine is an essential modulator of memory through its ability to regulate synaptic mechanisms. Emotional arousal leads to activation of the locus coeruleus with the subsequent release of norepineprine in the brain, resulting in the enhancement of memory. Norepinephrine activates both pre- and post-synaptic adrenergic receptors at central synapses with different functional outcomes, depending on the expression pattern of these receptors in specific neural circuitries underlying distinct behavioral processes. We review the evidence for noradrenergic modulation of synaptic plasticity with consideration of how this may contribute to the mechanisms of learning and memory. |
Twitter Demographics
The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| Japan | 1 | 20% |
| Canada | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 434 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | <1% |
| Germany | 4 | <1% |
| United Kingdom | 4 | <1% |
| France | 2 | <1% |
| Canada | 2 | <1% |
| Turkey | 1 | <1% |
| Italy | 1 | <1% |
| Switzerland | 1 | <1% |
| India | 1 | <1% |
| Other | 6 | 1% |
| Unknown | 408 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 102 | 24% |
| Student > Bachelor | 69 | 16% |
| Student > Master | 59 | 14% |
| Researcher | 54 | 12% |
| Student > Doctoral Student | 22 | 5% |
| Other | 72 | 17% |
| Unknown | 56 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 104 | 24% |
| Neuroscience | 96 | 22% |
| Psychology | 62 | 14% |
| Medicine and Dentistry | 34 | 8% |
| Biochemistry, Genetics and Molecular Biology | 17 | 4% |
| Other | 50 | 12% |
| Unknown | 71 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 56. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2023.
All research outputs
#710,326
of 24,309,087 outputs
Outputs from Molecular Brain
#13
of 1,170 outputs
Outputs of similar age
#2,575
of 171,241 outputs
Outputs of similar age from Molecular Brain
#1
of 4 outputs
Altmetric has tracked 24,309,087 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,170 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 171,241 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them