Effects of PCSK9 inhibitors on all-cause mortality (38-RCT systematic review & meta-analysis) – All-cause mortality and cardiovascular mortality were not reduced by treatment with #PCSK9 inhibitors (MH-OR=0.94; 0.84/1.04 and OR=0.97; 0.86/1.09]) https:
@ThelastStyleb16 @ZahcM "All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors (MH-OR 0.94 [0.84, 1.04] and 0.97[0.86;1.09])" https://t.co/BEbpYNuB5Q
@VerenaMaria82 "The number needed to treat for 2 years for preventing one event was 89. All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors (MH-OR 0.94 [0.84, 1.04] and 0.97[0.86;1.09])." https://t.co/DPB0
@ArtirKel ...and on meta-analysis of PCSk-9 inhibition RCTs, no effect on all-cause mortality. I have invested little time into LDL literature, so please correct me if I'm misguided, but when considering the Taeuber paradox, does LDL really matter for ag
RT @DiscoStew66: “All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors” 🤔 https://t.co/1r…
“All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors” 🤔 https://t.co/1rMwNCJ3PX
RT @DiscoStew66: “All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors” 🤔 https://t.co/ne…
RT @DiscoStew66: “All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors” 🤔 https://t.co/ne…
RT @DiscoStew66: “All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors” 🤔 https://t.co/ne…
“All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors” 🤔 https://t.co/neVDPfIZ6f
@DaveKeto @OhhiyoGarmen @holmanm @kevinnbass @DrPaulMason @Drlipid @PeterAttiaMD @FatEmperor @POhukainen @ckjellmo @ArsenaultBenoit Null results also hold in meta-analyses for mortality endpoints - https://t.co/dh0l8fRpp6 https://t.co/5IAyXnFhoO
RT @DiscoStew66: And you take a PCSK-9 inhibitor why exactly? “All-cause mortality and cardiovascular mortality were not reduced by treatm…
RT @DiscoStew66: And you take a PCSK-9 inhibitor why exactly? “All-cause mortality and cardiovascular mortality were not reduced by treatm…
RT @DiscoStew66: And you take a PCSK-9 inhibitor why exactly? “All-cause mortality and cardiovascular mortality were not reduced by treatm…
And you take a PCSK-9 inhibitor why exactly? “All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors...” https://t.co/d3x5vDp8Dy
RT @DiscoStew66: “Available data do not suggest any relevant effect of PCSK-9 inhibitors either on cardiovascular or all-cause mortality.”…
“Available data do not suggest any relevant effect of PCSK-9 inhibitors either on cardiovascular or all-cause mortality.” https://t.co/d3x5vDp8Dy https://t.co/0KMSWRldHV
@ZahcM @eatmostlyfatali I forgot that it was just MACE not CVD mortality: https://t.co/8R8WutzzPQ
RT @ZahcM: Evidence today based on better but still likely biased trials: pathetic benefit on CV events and no benefits on CV mortality and…
@tonytony1316131 Association only seen in very-high risk subjects. Little to no association was seen in lower risk subjects with similar reductions in LDL. I prefer mortality. Randomized comparisons show no benefit on CVD death or total mortality with PS
RT @ZahcM: Evidence today based on better but still likely biased trials: pathetic benefit on CV events and no benefits on CV mortality and…
Evidence today based on better but still likely biased trials: pathetic benefit on CV events and no benefits on CV mortality and all-cause death - https://t.co/KX5a6FMCdZ https://t.co/U5ixvRoG5s
@CCees @Bartissimus @nhgnieuws @volkskrant @FarmaTweets LDL-verlaging is een pseudo eindpunt: PCSK9-remmers verlagen LDL heel sterk maar hebben geen effect op mortaliteit. “All-cause mortality and cardiovascular mortality were not reduced by treatment with
@caseofdees @guido_vogel @FrankvanWijck @DiabetesDietist @vankarine @JanetNoome @jaapseidell Ook dat is niet vrij van discussie: PCSK9-remmers bijvoorbeeld. “All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibit
"All-cause mortality and cardiovascular mortality were not reduced by treatment with PCSK-9 inhibitors." https://t.co/8R8WutzzPQ
RT @NNTonthefly: New NNT→Effects of PCSK9 inhibitors on LDL cholesterol, cardiovascular morbidity and all-cause mortality: a systematic rev…
RT @NNTonthefly: New NNT→Effects of PCSK9 inhibitors on LDL cholesterol, cardiovascular morbidity and all-cause mortality: a systematic rev…
New NNT→Effects of PCSK9 inhibitors on LDL cholesterol, cardiovascular morbidity and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials. https://t.co/9hd6HAd3aO