Immune dysfunction as a precursor to neurodegeneration is revealed partly through GWAS. It's remarkable that interleukin is implicated in delirium GWAS for example. There is a molecular basis to some aspects of delirium. https://t.co/7PVq9elIwD
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. New locus at chromosome 7q36 within the DPP6 gene led by rs118113626. htt
A study based on the largest cohort of unrelated FTLD-TDP patients to date provides a comprehensive view of the genetic landscape of FTLD-TDP, nominates novel FTLD-TDP risk loci and strongly implicates the immune pathway in FTLD-TDP pathogenesis: https://t
RT @Neuro_Genomics: In another collaborative effort, and using whole genome sequencing data we identified additional novel risk genes for…
RT @Neuro_Genomics: In another collaborative effort, and using whole genome sequencing data we identified additional novel risk genes for…
In another collaborative effort, and using whole genome sequencing data we identified additional novel risk genes for Frontotemporal lobar degeneration. https://t.co/GV7pdm7CjI Interestingly, and as in the case of #Alzheimer these genes also point out to
#ICYMI The dysfunction of the immune system may contribute to the pathogenesis of #FTD suggesting that immunomodulators may be of benefit in at least some forms of the disease https://t.co/1iIEcHm3zs #CHMP2B #TDP43 #UNC13A #TBK1 @SpringerPath via @Shorter
Possible role for genes functioning within the TBK1-related immune pathway (e.g., DHX58, TRIM21, IRF7) in the genetic etiology of FTLD-TDP: https://t.co/vXNKZvNlgX
RT @UCSFmac: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk facto…
RT @NeuroGen_papers: PubMed: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel di…
RT @NeuroGen_papers: PubMed: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel di…
RT @BrainMind_Usyd: #Research alert #USydBMC Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium…
RT @BrainMind_Usyd: #Research alert #USydBMC Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium…
RT @UCSFmac: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk facto…
#Research alert #USydBMC Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. https://t.co/9ooxzJlDqH #FTP #Frontotemporal #de
RT @NatRevNeurol: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk…
PubMed: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. https://t.co/feX791aXB9
RT @UCSFmac: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk facto…
RT @UCSFmac: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk facto…
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. https://t.co/ao0eui8G90 https://t.co/vkZ5OkWBGi
RT @NatRevNeurol: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk…
RT @NatRevNeurol: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk…
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. https://t.co/JvckACN7te
RT @NatRevNeurol: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk…
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD https://t.co/UVmLhmsZyn
RT @NeuropathClinic: Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease ri…
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. #neuropath https://t.co/1JErIyvSOA