@Tapani1_ Yes it's possible that Covid vaccination is having a "trained immunity" effect more like inactivated flu vaccines than live vaccines (as one might have expected from mRNA). https://t.co/SZ8xChbqjv
by reprogramming innate immunity (which is generic for all pathogens) to be less sensitive. Live attenuated vaccines often do the opposite. Another possible mechanism (which has not been explored in specific detail for flu vaccines to my knowledge)... htt
@FlyingAlpaka @CellCellPress @GaviSeth We compared the old smallpox vaccine and modified Vaccinia Ankara for their innate immune training effects; they differered, as only the old vaccine induced trained innate immunity. https://t.co/NNvHbwY5ce
RT @StabellBenn: Links to relevant papers: Smallpox vaccine and mortality: https://t.co/UoUl93Ok6d https://t.co/AaNoI1FmDa https://t.co/u…
RT @StabellBenn: Links to relevant papers: Smallpox vaccine and mortality: https://t.co/UoUl93Ok6d https://t.co/AaNoI1FmDa https://t.co/u…
RT @StabellBenn: Links to relevant papers: Smallpox vaccine and mortality: https://t.co/UoUl93Ok6d https://t.co/AaNoI1FmDa https://t.co/u…
RT @StabellBenn: Links to relevant papers: Smallpox vaccine and mortality: https://t.co/UoUl93Ok6d https://t.co/AaNoI1FmDa https://t.co/u…
RT @StabellBenn: Links to relevant papers: Smallpox vaccine and mortality: https://t.co/UoUl93Ok6d https://t.co/AaNoI1FmDa https://t.co/u…
Links to relevant papers: Smallpox vaccine and mortality: https://t.co/UoUl93Ok6d https://t.co/AaNoI1FmDa https://t.co/uEqMpq7snE Smallpox vaccine and HIV: https://t.co/xakCbrbMEI The effects of old and new smallpox vaccines on the innate immune system:
RT @StabellBenn: Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the…
RT @StabellBenn: Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the…
RT @StabellBenn: Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the…
RT @StabellBenn: Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the…
RT @StabellBenn: Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the…
RT @StabellBenn: Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the…
Bas has made a major contribution to science by showing that live and non-live vaccines have very different effects on the innate immune system (live induce training, non-live tolerance) - and their sequence matters. Linking to some key papers here #NSEvac
@R4nd4hl @AntonAAAutzen Studiet lægger sig i en række af studier, der har vist, at levende vacciner inducerer innate immun træning, mens ikke-levende gør det modsatte. Eksemplificeret her i et studie, hvor vi testede levende og ikke-levende koppevaccine. h
Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity. https://t.co/VIMjlfiAap
RT @StabellBenn: Another paper on live/non-live vaccine differences in collaboration with @Sander_Lab: https://t.co/LfIeQ3GIUV https://t.co…
Another paper on live/non-live vaccine differences in collaboration with @Sander_Lab: https://t.co/LfIeQ3GIUV
Getting closer to explain differences in overall mortality effects of live and non-live vaccines (https://t.co/WvN9UUh4pC): "Vaccinia induces trained immunity in vitro, whereas MVA [Modified Vaccinia Ankara] induces innate immune tolerance" https://t.co/Nj