Also this from 2019: 👀👇🏼. Claudin-5: gatekeeper of neurological function | Fluids and Barriers of the CNS | Full Text https://t.co/nnAF1rHyH6
@P_McCulloughMD It would be nice to see if people with neurologic and endothelial damage, plus some cancers, had elevated Claudin-5 autoantibodies. Perhaps if found, they could be removed. https://t.co/rPSjXGnUBB
@louietraub @michellespj And found these articles. The 1st could explain why some drugs might make things worse, if blood-brain barrier is disrupted. Also could account for endothelial damage. Maybe could test for/remove it? I wish there were studies. htt
The Importance of "Claudin-5" in the Brain The blood–brain barrier (BBB) is formed by a tightly packed layer of endothelial cells lining the brain capillaries Tight junction proteins of the blood–brain barrier are vital for maintaining.. https://t.co/oxmC
RT @TyQuig: The human BBB provides "~12 m^2 of endothelial surface for molecular exchange and an approx 1:1 ratio of capillaries to neurons…
The human BBB provides "~12 m^2 of endothelial surface for molecular exchange and an approx 1:1 ratio of capillaries to neurons..." That is MIND-boggling. Super curious how nutrients are transported throughout the insect brain, which don't have capillarie
Some light reading material! New review on the blood-brain barrier and claudin-5 in neurological disorders. https://t.co/88UEYr9683