@ejustin46 @KatePri14608408 @NjbBari3 If there's nothing on COVID, perhaps other feline enteric virus care/treatments might yield clues. Beyond coronaviruses, other members of Pisuviricota might be worth looking at with respect to co-infection, reactivatio
Why would an anti-fungal drug (itraconazole) be a viable treatment for feline coronavirus infection? ¯\_(ツ)_/¯ "In this study, we demonstrated that itraconazole (ICZ), practically used for fungal infections in cats, inhibits the type I FCoV infection." ht
@trevor7979 My cat had cat coronavirus. Holistic MD/cat rescuer friend advised ITRACONAZOLE, provided this study: https://t.co/ssgEm1JeJN He said: "I was surprised an antifungal showed antiviral properties. Has to do with cholesterol metabolism - it's a c
@DrPalmquist
RT @__ice9: @drakchaurasia @Thinkerks @Aguirre1Gustavo @DrSubhasree Itraconazole also works against a variety of other encapsulated viruses…
@Virusemergentes @joevaron Pulse treatment with itraconazole could be a complement to ivermectin treatment, it has already demonstrated efficacy against feline coronavirus and SARS-Cov-2 https://t.co/uJOdwfcYPd
@__ice9 @cvamarosa @monarchdiaries @Regeneron Do you happen to have papers on why you think itraconazole would work as antiviral? I have read [1] https://t.co/Vpa2pJaapE and also [2] https://t.co/9LBAFf7GOK [1] Is for influenza and [2] examines its a
@neorevolt @zzz_as_zzz See this post and the one that it quotes. https://t.co/AXbiOurj7H
@ulc2020 @p7p8p9p @drakchaurasia @Thinkerks @Aguirre1Gustavo @DrSubhasree We only recently saw hard evidence that itraconazole works in vitro against SARS-CoV-2 at clinically attainable concentrations-- though it does have earlier evidence against other re
RT @__ice9: @drakchaurasia @Thinkerks @Aguirre1Gustavo @DrSubhasree Itraconazole also works against a variety of other encapsulated viruses…
@drakchaurasia @Thinkerks @Aguirre1Gustavo @DrSubhasree Itraconazole also works against a variety of other encapsulated viruses. It appears to interfere with cellular cholesterol trafficking in a manner that inhibits membrane fusion with the virus. https
RT @__ice9: @zzz_as_zzz @farid__jalali @gstanchev Relatedly, itraconazole is a cholesterol trafficking inhibitor and blocks membrane fusion…
@zzz_as_zzz @farid__jalali @gstanchev Relatedly, itraconazole is a cholesterol trafficking inhibitor and blocks membrane fusion by various encapsulated viruses. https://t.co/mYjXwD7r2w https://t.co/J6sRYiPUFv https://t.co/KufbD9aIRd https://t.co/LjkHz5
RT @cvamarosa: @navedelmisterio En gatos con coronavirus empleamos con éxito el itraconazol, https://t.co/uJOdwfcYPd antifúngico con efec…
RT @cvamarosa: @RicardLopez123 @BlasIgnacio El itraconazol actúa sobre la vía del interferón y proteínas transmembrana. Ya demostró eficaci…
RT @cvamarosa: @RicardLopez123 @BlasIgnacio El itraconazol actúa sobre la vía del interferón y proteínas transmembrana. Ya demostró eficaci…
@RicardLopez123 @BlasIgnacio El itraconazol actúa sobre la vía del interferón y proteínas transmembrana. Ya demostró eficacia en coronavirus felino (PIF) y lo acaba de hacer en SARSCov2 invitro https://t.co/9KXaxvZni1
@navedelmisterio En gatos con coronavirus empleamos con éxito el itraconazol, https://t.co/uJOdwfcYPd antifúngico con efecto sobre la vía del interferón y a denostado eficacia en el virus de las gripes y otros coronavirus como el MERS y el SARS https://t
@michikusajui 昨年の1月にpublishされてますね。FIPに抗真菌薬とか、Covid 19にイベルメクチンとか、もう何でもあり!の世界なのかなと思ってます。
Antiviral activity of itraconazole against type I feline coronavirus infection | Veterinary Research | Full Text https://t.co/H0956ek3du
Itraconazole anyone??!! (Depends how much homology there is between CoV for different species, but someone clever could have a look?) https://t.co/1jef4haWiL If it works, I'm claiming a victory over #ArtificialIntelligence which couldn't find this relat
Further on, how much homology is there between CoV for different species and can treatments proposed in one, be trialled in another ?? I'm going to be claiming a copyright here btw 😜 https://t.co/X4YEIv3yz0
@Pharmaheretic @monarchdiaries @so_many_ryans @lewistlc @aliostad @BioBreakout @aknappjr @YinPD @InceptionCap @hcornea @icedoc61 Itraconazole blocks cholesterol exit from late endosomes, disrupting their function somehow (details unclear) https://t.co/vw18
安定の北里大からのFIPの治療に抗人TNFα抗体を投与したという実験。 FIPの曰く付きの薬が闇に出回っている中、こうした一つ一つの研究の積み重ねが重要です。 Antiviral Activity of Itraconazole Against Type I Feline Coronavirus Infection - PubMed https://t.co/NJOlYHZnCg
@immuninfection Tendría sentido usarlo en el covid-19? Y farmacia que puedan bloquear los factores de elongacion (EF-1)o inhibidos de la síntesis proteica del paciente? https://t.co/e88FoMbCDj
@PrestonLewis8 Efficacy in an animal coronavirus model using similar mechanisms-- https://t.co/vw18jOwt67
Antiviral activity of itraconazole against type I feline coronavirus infection | Veterinary Research | Full Text https://t.co/I6GnPRyKuz
@margianta @adibahhanun Hi everybody! How's big warrior Teddy Going on? Found this and wanted to share. May be Itraconazol (antifungal drug) can help. https://t.co/Dh6xtScJiH
https://t.co/hjKh2ALXE4. @JamesEKHildreth - can you test Cyclo on the #WuhanCoronavirus? @AmyDMarcus
Antiviral activity of itraconazole against type I feline coronavirus infection https://t.co/uKrJFVLpA9
itraconazole, practically used for fungal infections in cats, inhibits the type I feline #coronaviruses infection, suggesting that itraconazole could potentially be used as a therapeutic https://t.co/jdUP80zLjj https://t.co/mgzbzEYGnS