Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas

This is a great review for anyone starting out working on the problem of Variants of Uncertain Significance (VUS) or clinical genetic variant modelling/interpretation in general. I really like the ClinVar graph illustrating the growing VUS challenge: https

JW: MAVE: Massively parallel assays of variant effect. #probgen18 https://t.co/whArj4lkiV https://t.co/hCTSEXladJ