@nataliaduquew @DayLabUAB @SvitlanaBach @scharfmanlab But, you get a completely opposing phenotype if TrkB is depleted in some GABAergic populations - we have shown this, and also great work in this space from Prince lab at Stanford https://t.co/qkwhWn0DFG
This work followed up on previous work from our lab showing that TrkB depletion from cortistatin-expressing cells causes severe, spontaneous seizures that result in premature death https://t.co/S7xcF9x713
Cortistatin-expressing interneurons require TrkB signaling to suppress neural hyper-excitability. https://t.co/pnanuXaOz0
🎉🎉
!! my name's on a paper https://t.co/xt4ScEHwaT
RT @martinowk: Excited that this orphan lab project (started as a postdoc!!) showing role of cortistatin-expressing interneurons in cortica…
RT @martinowk: Excited that this orphan lab project (started as a postdoc!!) showing role of cortistatin-expressing interneurons in cortica…
Congrats all!
RT @martinowk: Excited that this orphan lab project (started as a postdoc!!) showing role of cortistatin-expressing interneurons in cortica…
Excited that this orphan lab project (started as a postdoc!!) showing role of cortistatin-expressing interneurons in cortical excitability is finally in press: https://t.co/nniapC45xa Congrats @2scientistsin1 Thanks to @henry_hallock @TwitHardily @bradymah