Systems, methods, and compositions for site-specific genetic engineering using… Grant US-11952571-B2 United States of America 09 Apr 2024
High efficiency base editors comprising Gam Grant US-11932884-B2 United States of America 19 Mar 2024
Methods and compositions for simultaneous editing of both strands of a target double-strand… Grant US-11912985-B2 United States of America 27 Feb 2024
GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE Application WO-2024020346-A2 World Intellectual Property Organisation (WIPO) 25 Jan 2024
Delivery of CAS9 via ARRDC1-mediated microvesicles (ARMMs) Grant US-11827910-B2 United States of America 28 Nov 2023
Systems, methods, and compositions for site-specific genetic engineering using… Grant US-11827881-B2 United States of America 28 Nov 2023
Editing of CCR2 receptor gene to protect against HIV infection Grant US-11820969-B2 United States of America 21 Nov 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11795452-B2 United States of America 24 Oct 2023
Methods and compositions for evolving base editors using phage-assisted continuous… Grant US-11732274-B2 United States of America 22 Aug 2023
Delivery of therapeutic RNAs via ARRDC1-mediated microvesicles Grant US-11730823-B2 United States of America 22 Aug 2023
Adenosine nucleobase editors and uses thereof Grant US-11702651-B2 United States of America 18 Jul 2023
PROGRAMMABLE INSERTION APPROACHES VIA REVERSE TRANSCRIPTASE RECRUITMENT Application WO-2023114992-A1 World Intellectual Property Organisation (WIPO) 22 Jun 2023
Programmable CAS9-recombinase fusion proteins and uses thereof Grant US-11661590-B2 United States of America 30 May 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11643652-B2 United States of America 09 May 2023
METHODS AND COMPOSITIONS FOR EDITING A GENOME WITH PRIME EDITING AND A RECOMBINASE Application WO-2023076898-A1 World Intellectual Property Organisation (WIPO) 04 May 2023
CAS9 proteins including ligand-dependent inteins Grant US-11578343-B2 United States of America 14 Feb 2023
Systems, methods, and compositions for site-specific genetic engineering using… Grant US-11572556-B2 United States of America 07 Feb 2023
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and… Grant US-11560566-B2 United States of America 24 Jan 2023
Incorporation of unnatural amino acids into proteins using base editing Grant US-11542509-B2 United States of America 03 Jan 2023
CAS9 PROTEINS INCLUDING LIGAND-DEPENDENT INTEINS Application EP-4079847-A1 European Patent Office 26 Oct 2022
Methods and compositions for prime editing nucleotide sequences Grant US-11447770-B1 United States of America 20 Sep 2022
CRISPR-related methods and compositions with governing gRNAS Grant US-11390887-B2 United States of America 19 Jul 2022
High efficiency base editors comprising Gam Grant US-11319532-B2 United States of America 03 May 2022
SYSTEMS, METHODS, AND COMPOSITIONS FOR SITE-SPECIFIC GENETIC ENGINEERING USING… Application WO-2022087235-A1 World Intellectual Property Organisation (WIPO) 28 Apr 2022
Nucleobase editors comprising nucleic acid programmable DNA binding proteins Grant US-11268082-B2 United States of America 08 Mar 2022
METHODS AND COMPOSITIONS FOR SIMULTANEOUS EDITING OF BOTH STRANDS OF A TARGET DOUBLE-STRAND… Application WO-2021226558-A1 World Intellectual Property Organisation (WIPO) 11 Nov 2021
DELIVERY SYSTEM FOR FUNCTIONAL NUCLEASES Application EP-3848384-A1 European Patent Office 14 Jul 2021
Fusions of Cas9 domains and nucleic acid-editing domains Grant US-11053481-B2 United States of America 06 Jul 2021
Delivery of cargo proteins via ARRDC1-mediated microvesicles (ARMMs) Grant US-11001817-B2 United States of America 11 May 2021
Adenosine nucleobase editors and uses thereof Grant US-10947530-B2 United States of America 16 Mar 2021
ARRDC1-mediated microvesicles (ARMMS) and uses thereof Grant US-10945954-B2 United States of America 16 Mar 2021
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191233-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191239-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191241-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191242-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191243-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191246-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191245-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191234-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHOD AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191248-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES Application WO-2020191249-A1 World Intellectual Property Organisation (WIPO) 24 Sep 2020
Editing of CCR5 receptor gene to protect against HIV infection Grant US-10745677-B2 United States of America 18 Aug 2020
CAS9 proteins including ligand-dependent inteins Grant US-10704062-B2 United States of America 07 Jul 2020
NUCLEOBASE EDITORS COMPRISING GEOCAS9 AND USES THEREOF Application WO-2020092453-A1 World Intellectual Property Organisation (WIPO) 07 May 2020
CRISPR-related methods and compositions with governing gRNAs Grant US-10640788-B2 United States of America 05 May 2020
Methods for identifying a target site of a CAS9 nuclease Grant US-10508298-B2 United States of America 17 Dec 2019
Evaluation and improvement of nuclease cleavage specificity Grant US-10323236-B2 United States of America 18 Jun 2019
Delivery of cargo proteins via ARRDC1-mediated microvesicles (ARMMs) Grant US-10260055-B2 United States of America 16 Apr 2019
CRISPR-related methods and compositions with governing gRNAS Grant US-10190137-B2 United States of America 29 Jan 2019
EX VIVO MEAT PRODUCTION Application WO-2018227016-A1 World Intellectual Property Organisation (WIPO) 13 Dec 2018
Adenosine nucleobase editors and uses thereof Grant US-10113163-B2 United States of America 30 Oct 2018
CAS9 proteins including ligand-dependent inteins Grant US-10077453-B2 United States of America 18 Sep 2018
PROGRAMMABLE CAS9-RECOMBINASE FUSION PROTEINS AND USES THEREOF Application WO-2018031683-A1 World Intellectual Property Organisation (WIPO) 15 Feb 2018
CRISPR-related methods and compositions with governing gRNAS Grant US-9834791-B2 United States of America 05 Dec 2017
Delivery of CAS9 via ARRDC1-mediated microvesicles (ARMMs) Grant US-9816080-B2 United States of America 14 Nov 2017
ARRDC1-mediated microvesicles (ARMMs) and uses thereof Grant US-9737480-B2 United States of America 22 Aug 2017
DELIVERY OF NEGATIVELY CHARGED PROTEINS USING CATIONIC LIPIDS Application WO-2016070129-A1 World Intellectual Property Organisation (WIPO) 06 May 2016
Evaluation and improvement of nuclease cleavage specificity Grant US-9322006-B2 United States of America 26 Apr 2016
CAS9 PROTEINS INCLUDING LIGAND-DEPENDENT INTEINS Application WO-2016022363-A2 World Intellectual Property Organisation (WIPO) 11 Feb 2016
Methods for identifying a target site of a Cas9 nuclease Grant US-9163284-B2 United States of America 20 Oct 2015
Methods for correcting presenilin point mutations Application US-9068179-B1 United States of America 30 Jun 2015
DELIVERY SYSTEM FOR FUNCTIONAL NUCLEASES Application WO-2015035136-A2 World Intellectual Property Organisation (WIPO) 12 Mar 2015