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Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials

Overview of attention for article published in Annals of Biomedical Engineering, October 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#23 of 1,206)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
4 news outlets

Citations

dimensions_citation
1 Dimensions

Readers on

mendeley
8 Mendeley
Title
Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials
Published in
Annals of Biomedical Engineering, October 2015
DOI 10.1007/s10439-015-1489-y
Pubmed ID
Authors

Keith M. Faucher, Natalie Artzi, Moshe Beck, Rita Beckerman, Geoff Moodie, Theresa Albergo, Suzanne Conroy, Alicia Dale, Scott Corbeil, Paul Martakos, Elazer R. Edelman

Abstract

In vitro and in vivo studies were conducted on omega-3 fatty acid-derived biomaterials to determine their utility as an implantable material for adhesion prevention following soft tissue hernia repair and as a means to allow for the local delivery of antimicrobial or antibiofilm agents. Naturally derived biomaterials offer several advantages over synthetic materials in the field of medical device development. These advantages include enhanced biocompatibility, elimination of risks posed by the presence of toxic catalysts and chemical crosslinking agents, and derivation from renewable resources. Omega-3 fatty acids are readily available from fish and plant sources and can be used to create implantable biomaterials either as a stand-alone device or as a device coating that can be utilized in local drug delivery applications. In-depth characterization of material erosion degradation over time using non-destructive imaging and chemical characterization techniques provided mechanistic insight into material structure: function relationship. This in turn guided rational tailoring of the material based on varying fatty acid composition to control material residence time and hence drug release. These studies demonstrate the utility of omega-3 fatty acid derived biomaterials as an absorbable material for soft tissue hernia repair and drug delivery applications.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 25%
Student > Postgraduate 1 13%
Professor 1 13%
Student > Master 1 13%
Student > Ph. D. Student 1 13%
Other 2 25%
Readers by discipline Count As %
Unspecified 2 25%
Medicine and Dentistry 2 25%
Agricultural and Biological Sciences 1 13%
Chemistry 1 13%
Biochemistry, Genetics and Molecular Biology 1 13%
Other 1 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 33. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2015.
All research outputs
#422,952
of 12,356,791 outputs
Outputs from Annals of Biomedical Engineering
#23
of 1,206 outputs
Outputs of similar age
#15,514
of 327,128 outputs
Outputs of similar age from Annals of Biomedical Engineering
#1
of 31 outputs
Altmetric has tracked 12,356,791 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,206 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,128 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.