| Title |
The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases
|
|---|---|
| Published in |
Molecular and Cellular Pediatrics, February 2015
|
| DOI | 10.1186/s40348-015-0014-6 |
| Pubmed ID | |
| Authors |
Ines Mack, Andreas Hector, Marlene Ballbach, Julius Kohlhäufl, Katharina J Fuchs, Alexander Weber, Marcus A Mall, Dominik Hartl |
| Abstract |
Chitin, after cellulose, the second most abundant biopolymer on earth, is a key component of insects, fungi, and house-dust mites. Lower life forms are endowed with chitinases to defend themselves against chitin-bearing pathogens. Unexpectedly, humans were also found to express chitinases as well as chitinase-like proteins that modulate immune responses. Particularly, increased levels of the chitinase-like protein YKL-40 have been associated with severe asthma, cystic fibrosis, and other inflammatory disease conditions. Here, we summarize and discuss the potential role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases. |
X Demographics
The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 5% |
| Australia | 1 | 5% |
| Austria | 1 | 5% |
| Iceland | 1 | 5% |
| Barbados | 1 | 5% |
| Unknown | 17 | 77% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 1% |
| Unknown | 95 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 21% |
| Researcher | 14 | 15% |
| Student > Doctoral Student | 8 | 8% |
| Student > Bachelor | 8 | 8% |
| Student > Master | 7 | 7% |
| Other | 19 | 20% |
| Unknown | 20 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 22% |
| Biochemistry, Genetics and Molecular Biology | 20 | 21% |
| Medicine and Dentistry | 13 | 14% |
| Immunology and Microbiology | 10 | 10% |
| Engineering | 4 | 4% |
| Other | 5 | 5% |
| Unknown | 23 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2024.
All research outputs
#1,111,424
of 25,750,437 outputs
Outputs from Molecular and Cellular Pediatrics
#6
of 112 outputs
Outputs of similar age
#13,501
of 270,970 outputs
Outputs of similar age from Molecular and Cellular Pediatrics
#1
of 3 outputs
Altmetric has tracked 25,750,437 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 112 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has done particularly well, scoring higher than 94% of its peers.
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We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them