| Title |
The effect of disease burden on the speed of aging: an analysis of the Sardinian mortality transition
|
|---|---|
| Published in |
Genus, August 2018
|
| DOI | 10.1186/s41118-018-0028-8 |
| Pubmed ID | |
| Authors |
Giambattista Salinari, Gabriele Ruiu |
| Abstract |
According to the constant senescence hypothesis, senescence cannot be accelerated or decelerated by exogenous factors. Two contrasting theories have been proposed in the literature. According to the inflammaging theory, those individuals who have experienced a higher antigenic load will experience more rapid senescence. Instead, the calorie restriction theory stresses that excessive daily calorie intake can produce an acceleration in senescence. To test these theories, this paper analyzes the evolution of the rate of aging in Sardinia (Italy). In this population, the epidemiological transition started without any substantial modification in nutritional levels. This allows us to test the constant senescence hypothesis against the inflammaging theory, without the possible confounding effect produced by the nutrition transition. To accomplish this aim, the longitudinal life tables from 80 years onwards for Sardinian cohorts born between 1866 and 1908 were reconstituted. They were then used to estimate the rate of aging by means of the Gamma-Gompertz model. Coherently with the inflammaging theory, the results show that the Sardinian population experienced a dramatic decrease in the rate of aging that coincided with the onset of the epidemiological transition. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Canada | 1 | 25% |
| France | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Scientists | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 30% |
| Professor | 1 | 10% |
| Student > Ph. D. Student | 1 | 10% |
| Student > Master | 1 | 10% |
| Unknown | 4 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 1 | 10% |
| Business, Management and Accounting | 1 | 10% |
| Nursing and Health Professions | 1 | 10% |
| Agricultural and Biological Sciences | 1 | 10% |
| Immunology and Microbiology | 1 | 10% |
| Other | 1 | 10% |
| Unknown | 4 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2022.
All research outputs
#2,158,542
of 25,556,408 outputs
Outputs from Genus
#29
of 175 outputs
Outputs of similar age
#42,891
of 342,317 outputs
Outputs of similar age from Genus
#2
of 4 outputs
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So far Altmetric has tracked 175 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one has done well, scoring higher than 84% of its peers.
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