14/ Despite being rare in NDMM, IgH-MAF translocations are common in cell lines, demonstrating the ability of these cells to survive outside the BM w/ high rates of EMD and PCL. Qiang, et al, also found that MAFb confers resistance to PIs in cell lines htt
RT @1MIRT: Check out the recent publication from Myeloma Institute researcher, Ya-Wei Qiang, M.D., Ph.D., " MAFb protein confers intrinsic…
RT @1MIRT: Check out the recent publication from Myeloma Institute researcher, Ya-Wei Qiang, M.D., Ph.D., " MAFb protein confers intrinsic…
Check out the recent publication from Myeloma Institute researcher, Ya-Wei Qiang, M.D., Ph.D., " MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma." High MAFb protein expression has been... https://t.co/mF6a5OI1uH
MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma. https://t.co/30limO2S9O.
In #myeloma pre-clinical models, proteasome inhibitors including #Velcade and #Kyprolis induced stabilization of MAFb, which in turn conferred resistance to proteasome inhibitors: https://t.co/y19KrOgQ4o. https://t.co/MxrSEp6Eo8
PC | MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma. https://t.co/60a6wBR5D8