“Rapamycin reduces severity of senile osteoporosis, at least in part, by activating osteocyte autophagy….Therefore, rapamycin might be a feasible therapeutic approach for senile osteoporosis.” https://t.co/t7aUydIejl
RT @agingdoc1: Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy https://t.co/dxLCLEUUOG
RT @agingdoc1: Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy https://t.co/dxLCLEUUOG
RT @agingdoc1: Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy https://t.co/dxLCLEUUOG
Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy https://t.co/dxLCLEUUOG
Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy (2016) https://t.co/aDqoAiqwZz
Also neglected in the paper and Tweet was data from multiple studies showing that rapamycin in aged mice and rats can reverse age-associated bone loss. https://t.co/RrrStMQwFP /5
@agingdoc1 @NathanielEDavid @LammingLab Two examples: Periodontal bone in *aged* mice: https://t.co/doEepY9hPk Trabecular bone in *aged* rats: https://t.co/zEo2VYFijZ
ラパマイシンは、オステオサイトのオートファジーを誘導することで、加齢性骨粗鬆症を軽減する。 https://t.co/3Ak4hgzOhg ※24週齢雄SDラットを用いた実験。 mTOR阻害活性のあるカテキン類が、この経路を動かしてたら面白いなぁ✨
[Ost Int] Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy: Abstract ... https://t.co/8HyR54rG4t
RT @Osteoporose_NL: #Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy in aged rats http://t.co/nsjLEAoVEt
#Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy in aged rats http://t.co/nsjLEAoVEt
Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy. http://t.co/z9THXnZOXN http://t.co/6ozKF8ElOq