Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes: a randomised controlled trial

@ProfDFrancis Thanks for joining in, Professor The group has a long history of doing fantastic trials - pretty large - all PROBE - all bedtime dosing of BP meds - all positive See a partial list: https://t.co/ujsyeA2qCA

@Kidneys1st @KatieKwonMD Or see this It always works in this groups hands https://t.co/ujsyeA2qCA

@MikeRoseMDMPH @ChrisDJacksonMD @ProfHayward yup on latter aspect, see this thread https://t.co/sf76JT2aP6

@jaredvh @thebyrdlab They have not done a single negative trial ever https://t.co/1EcmQx4ZZT

@mikejohansenmd @AJSharmaMD @DrWayneAltman indeed also see this thread https://t.co/sf76JT2aP6 they have reported wonderful results with bedtime dosing of everything totally implausible

@cg_dr They have a long history of fantastic results https://t.co/1EcmQx4ZZT

@MLGumz @brandimwynne @NephroMD This same group has recruited tons of patients and done tons of studies from a single centre Bedtime dosing always works in their hands It’s a miracle! See thread https://t.co/ujsyeA2qCA

@kdinbburg @thebyrdlab @DustinGrowick See thread here of their track record https://t.co/ujsyeA2qCA

@VPrasadMDMPH @TomPMarshall The authors have a remarkably successful track record. They recruit large numbers and deliver positive outcomes. Same intervention See thread 1: https://t.co/ujsyeA2qCA

RT @hswapnil: @ProfHayward @thebyrdlab They shown many other implausible effects before See thread https://t.co/ujsyeA2qCA

@ProfHayward @thebyrdlab They shown many other implausible effects before See thread https://t.co/ujsyeA2qCA

RT @hswapnil: @Endoananth @CMClase @ESC_Journals @escardio @TomLuscher Not just one or two Here’s a longer list of their incredible findin…

@Endoananth @CMClase @ESC_Journals @escardio @TomLuscher Not just one or two Here’s a longer list of their incredible findings so far: https://t.co/ujsyeA2qCA

@EricTopol @ESC_Journals I fully agree, see also https://t.co/kjJIMe4G7O & https://t.co/mObr8DfwFt

@ProfHschneider Absolut Ihrer Meinung, siehe auch https://t.co/kjJIMe4G7O & https://t.co/mObr8DfwFt

@georgeta @raj_mehta And they have published an impressive body of positive RCTs with bedtime dosing See this thread from before https://t.co/ujsyeA2qCA

lets see more fascinating results: Bedtime dosing reduces incident CKD, N = 2078 RCT https://t.co/rH4zqlWkgQ Bedtime dosing reduces development of DM N = 2012 RCT https://t.co/U09JXPSthO Bedtime dosing reduces MACE in CKD N = 661 RCT https://t.co/ncWA

I must have missed this gem when it came out in 2016!! In HTN patients without DM, bedtime ingestion of a RAAS-modulating anti-hypertensive drug reduces the risk of new-onset type-2 diabetes (hazard ratio of 0.43 (0.31, 0.61)). https://t.co/rz53BV3wGW @Dia

RT @unicipa: Možda preterano, ali nema razloga ne pokušati: uzimanje ACEi ili ARB za pritisak pre spavanja smanjuje rizik za dijabetes. htt…

Možda preterano, ali nema razloga ne pokušati: uzimanje ACEi ili ARB za pritisak pre spavanja smanjuje rizik za dijabetes. https://t.co/vO4AlETEMY

INTERESANTE https://t.co/hNGqKHiyRW

RT @HecmagsMD: When ACEi/ARB moved to bedtime, there is 57% reduction in the risk of new-onset DM. https://t.co/NZMag4MfLj Any thoughts? ht…

RT @HecmagsMD: When ACEi/ARB moved to bedtime, there is 57% reduction in the risk of new-onset DM. https://t.co/NZMag4MfLj Any thoughts? ht…

RT @HecmagsMD: When ACEi/ARB moved to bedtime, there is 57% reduction in the risk of new-onset DM. https://t.co/NZMag4MfLj Any thoughts? ht…

Interesting but not sure how to explain https://t.co/LqBOYzOcSe

When ACEi/ARB moved to bedtime, there is 57% reduction in the risk of new-onset DM. https://t.co/NZMag4MfLj Any thoughts? https://t.co/2HsACzrMgk

Taking antihypertensives at associated with improved ambulatory blood pressure control https://t.co/t3XMlIwv7r

Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes Hermida et al https://t.co/Tb5gV8qhI6

RT @DiabetologiaJnl: Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes Hermida et al https://t.co…

RT @DiabetologiaJnl: Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes Hermida et al https://t.co…

Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes Hermida et al https://t.co/Tb5gV8qhI6

Take blood pressure meds at night for better control and less risk of diabetes (!)...even diuretics. https://t.co/ZckBSw2B7q

Blood Pressure Medication at Night Lowers Diabetes Risk http://t.co/QUxH991qvb

RT @MetaHICN: Taking #hypertension drugs at bedtime reduces risk of developing T2 #diabetes in new RCT @EASDnews http://t.co/LrE4HqaI8I

RT @MetaHICN: Taking #hypertension drugs at bedtime reduces risk of developing T2 #diabetes in new RCT @EASDnews http://t.co/LrE4HqaI8I

RT @syuichiao: 糖尿病歴のない高血圧患者2012人(平均52.7歳)を対象に降圧薬を起床時服用、就寝前服用を比較し新規糖尿病発症を比較したランダム化比較試験。新規糖尿病発症は就寝前服用で有意に低い。http://t.co/0L7trtM5LH

Taking #hypertension drugs at bedtime reduces risk of developing T2 #diabetes in new RCT @EASDnews http://t.co/LrE4HqaI8I

RT @syuichiao: 糖尿病歴のない高血圧患者2012人(平均52.7歳)を対象に降圧薬を起床時服用、就寝前服用を比較し新規糖尿病発症を比較したランダム化比較試験。新規糖尿病発症は就寝前服用で有意に低い。http://t.co/0L7trtM5LH

糖尿病歴のない高血圧患者2012人(平均52.7歳)を対象に降圧薬を起床時服用、就寝前服用を比較し新規糖尿病発症を比較したランダム化比較試験。新規糖尿病発症は就寝前服用で有意に低い。http://t.co/0L7trtM5LH

未読論文メモ ［降圧薬、2型糖尿Diabetologia］ http://t.co/0L7trtM5LH ［COPD増悪Chest］ http://t.co/Uc21iuqo8m ［STARTクライテリア］ http://t.co/uj79aobWPJ

RT @luisotobajas: La toma de medicamentos antes de acostarse para la hipertensión reduce el riesgo de diabetes tipo 2. http://t.co/I00ccx…

La toma de medicamentos antes de acostarse para la hipertensión reduce el riesgo de diabetes tipo 2. http://t.co/I00ccx6kNv

RT @DiabetologiaJnl: Taking blood pressure drugs at bedtime lowers diabetes risk http://t.co/Tb5gV8HT6G @DiabetologiaJnl @EASDnews #Diabeto…

Taking blood #pressure-lowering drugs at bedtime instead of morning lowers risk for type 2 #diabetes.... http://t.co/puUMHd6lrp

What time of day to take #hypertension meds? http://t.co/fHTDSM2sqy Early data shows #bedtime may be best to decr ambulatory blood pressure

RT @alfonso_casi: La toma de medicamentos antes de acostarse para la hipertensión reduce el riesgo de diabetes tipo 2. Este ensayo... http:…

La toma de medicamentos antes de acostarse para la hipertensión reduce el riesgo de diabetes tipo 2. Este ensayo... http://t.co/WczTppaafo

RT @luisrpadial: Por la noche, mejor...Hypertension medication before bedtime reduces diabetes risk. http://t.co/Wz9qpCpNR3 http://t.co/CKX…

RT @luisrpadial: Por la noche, mejor...Hypertension medication before bedtime reduces diabetes risk. http://t.co/Wz9qpCpNR3 http://t.co/CKX…

Por la noche, mejor...Hypertension medication before bedtime reduces diabetes risk. http://t.co/Wz9qpCpNR3 http://t.co/CKXIb1PjGY

RT @Office_j: 【就寝前降圧薬服用で糖尿病新規発症抑制の可能性。補正後HR 0.43 [95%CI 0.31 - 0.61 vs 起床後服用]。RA系抑制薬とβ遮断薬で抑制著明：2012例 5.9年観察】 Diabetologia https://t.co/TcMq…

RT @DiabetologiaJnl: Taking blood pressure drugs at bedtime lowers diabetes risk http://t.co/Tb5gV8HT6G @DiabetologiaJnl @EASDnews #Diabeto…

RT @DiabetologiaJnl: Taking blood pressure drugs at bedtime lowers diabetes risk http://t.co/Tb5gV8HT6G @DiabetologiaJnl @EASDnews #Diabeto…

Taking blood pressure drugs at bedtime lowers diabetes risk http://t.co/Tb5gV8HT6G @DiabetologiaJnl @EASDnews #Diabetologia #diabetes

RT @Office_j: 【就寝前降圧薬服用で糖尿病新規発症抑制の可能性。補正後HR 0.43 [95%CI 0.31 - 0.61 vs 起床後服用]。RA系抑制薬とβ遮断薬で抑制著明：2012例 5.9年観察】 Diabetologia https://t.co/TcMq…

Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes http://t.co/7HWtW6VA2k

Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes http://t.co/iobzQXLiu9

Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes http://t.co/xjiltAsB0r

Taking blood pressure drugs at night ↓diabetes risk http://t.co/ngJRGSTu1t http://t.co/FzrEnYIJog @DiabetologiaJnl http://t.co/BXOGGjcSIA

【就寝前降圧薬服用で糖尿病新規発症抑制の可能性。補正後HR 0.43 [95%CI 0.31 - 0.61 vs 起床後服用]。RA系抑制薬とβ遮断薬で抑制著明：2012例 5.9年観察】 Diabetologia https://t.co/TcMql25rv0