Double edged sword. 1. PPAR(s) & receptor density correlates (ACE2) PPARγ "agonist, increases ACE2" 2. "PPARs have been shown to regulate T-cell survival, activation, and CD4+ T helper cell differentiation into the Th1, Th2, Th17, and Treg lineages" h
RT @shaghayeghharbi: Similarly which transcription factors; signalling pathways; & niche-specific cues/milieu/social network -> beautifully…
The Nuclear Receptor PPARs as Important Regulators of T-Cell Functions and Autoimmune Diseases https://t.co/ID2WgmZhD4
-> Taste of Cherry (& PPARγ) (Ref. April 21 tweet) -> And keep in mind (tumor microenvironment) -> prosurvival factors/inflammatory/anti-inflammatory factors (aka Taste of Cherry) (Ref. April 22 tweet) https://t.co/uGpd8SiaS9
Similarly which transcription factors; signalling pathways; & niche-specific cues/milieu/social network -> beautifully orchestrated switch in immune system development -> wishbone curves/assays https://t.co/uGpd8SiaS9
-> For example, "PPARs have been shown to regulate T-cell survival, activation, and CD4+ T helper cell differentiation into the Th1, Th2, Th17, and Treg lineages" https://t.co/tryKBH0iLU