| Title |
Efficacy and safety of over-the-counter whitening strips as compared to home-whitening with 10 % carbamide peroxide gel—systematic review of RCTs and metanalysis
|
|---|---|
| Published in |
Clinical Oral Investigations, August 2015
|
| DOI | 10.1007/s00784-015-1547-8 |
| Pubmed ID | |
| Authors |
Carla Regina Serraglio, Luana Zanella, Karine Battestin Dalla-Vecchia, Sinval Adalberto Rodrigues-Junior |
| Abstract |
The study aims to compare the efficacy and safety of over-the-counter whitestrips with the American Dental Association (ADA)-recommended home-whitening using the 10 % carbamide peroxide gel. Randomized controlled trials (RCTs) comparing the clinical efficacy and safety of the whitestrips with the 10 % carbamide peroxide (10 % CP) gel applied on tray for tooth whitening in adults were searched at PubMed and Cochrane Central Register of Controlled Trials databases and selected up to October 2014. Efficacy of the whitening techniques was assessed through ∆E, ∆L, and ∆b parameters, while side effects were analyzed as dichotomous variables. Data was extracted independently by two reviewers. Metanalysis was performed using random- and fixed-effect models (RevMan 5.3). Eight studies were included in the metanalysis. The metanalysis revealed no significant difference between the intervention groups for tooth-whitening efficacy measured as ΔE (mean difference [MD]-0.53; 95 % CI [-1.72;0.66]; Z = 0.88; p = 0.38) and ΔL (MD-0.22; 95 % CI [-0.81;0.36]; z = 0.75; p = 0.45); reduction of yellowing was higher with the whitestrips (MD-0.47; 95 % CI [-0.89; -0.06]; Z = 2.25; p = 0.02). Tooth sensitivity (risk ratio [RR] 1.17; 95 % CI [0.81-1.69]; Z = 0.81; p = 0.42) and gingival sensitivity (RR 0.76; 95 % CI [0.53-1.10]; Z = 1.44; p = 0.15) were similar, regardless of the whitening method used. The observed gingival irritation was higher when the 10 % CP gel was applied on tray (RR 0.43; 95 % CI [0.20-0.93]; Z = 2.14; p = 0.03). The quality of evidence generated was rated very low for all outcomes. There is no sound evidence to support the use of the whitening strips in detriment of the ADA-recommended technique based on the 10 % carbamide peroxide gel applied on tray. To the moment, there is no sound evidence in dental literature to suggest that the ADA-recommended whitening technique based on 10 % carbamide peroxide gel could be substituted by the whitening strips. The existing studies, with their limitations, revealed similar tooth whitening and tooth and gingival sensitivity for both whitening techniques. |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Uruguay | 1 | <1% |
| Unknown | 110 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 12% |
| Student > Postgraduate | 11 | 10% |
| Student > Bachelor | 8 | 7% |
| Researcher | 6 | 5% |
| Student > Doctoral Student | 6 | 5% |
| Other | 22 | 20% |
| Unknown | 45 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 53 | 48% |
| Agricultural and Biological Sciences | 5 | 5% |
| Unspecified | 1 | <1% |
| Biochemistry, Genetics and Molecular Biology | 1 | <1% |
| Chemistry | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 49 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2018.
All research outputs
#2,464,191
of 22,821,814 outputs
Outputs from Clinical Oral Investigations
#55
of 1,406 outputs
Outputs of similar age
#33,713
of 264,084 outputs
Outputs of similar age from Clinical Oral Investigations
#2
of 29 outputs
Altmetric has tracked 22,821,814 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,406 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 96% of its peers.
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We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.