Corticobasal degeneration with TDP-43 pathology presenting with progressive supranuclear palsy syndrome: a distinct clinicopathologic subtype

#NewPub: Corticobasal degeneration with TDP-43 pathology presenting with progressive supranuclear palsy syndrome: a distinct clinicopathologic subtype https://t.co/D3DxClByAf

Corticobasal degeneration (CBD) is a clinically heterogeneous tauopathy, has overlaps w/ clinicopathologics & genetics of progressive supranuclear palsy (similar 2 #Parkinsons). New research indicates that severe TDP-43 pathology = distinct subtype of

RT @full_invest: TDP-43病理をもつCBDについて。 ・CBDの45％にTDP-43病理を認め、中脳被蓋、視床下核で頻度が高かった ・TDP病理が高度な例ではPSPと診断される率が高い（80％） ・下方注視麻痺が生前PSP診断根拠となることが多く、この所見は…

TDP-43病理をもつCBDについて。 ・CBDの45％にTDP-43病理を認め、中脳被蓋、視床下核で頻度が高かった ・TDP病理が高度な例ではPSPと診断される率が高い（80％） ・下方注視麻痺が生前PSP診断根拠となることが多く、この所見は中脳被蓋のTDP病理と関連が強い https://t.co/FqZwCCMaXY

Acta Neuropathologica誌 TDP-43陽性CBDはPSPタイプの臨床症状を呈しやすい。中脳のTDP病理が下方注視麻痺に関連している可能性。 https://t.co/jEax64VeNi

RT @NeuropathClinic: "Corticobasal degeneration with TDP-43 pathology presenting with progressive supranuclear palsy syndrome: a distinct c…

RT @NeuropathClinic: "Corticobasal degeneration with TDP-43 pathology presenting with progressive supranuclear palsy syndrome: a distinct c…

"Corticobasal degeneration with TDP-43 pathology presenting with progressive supranuclear palsy syndrome: a distinct clinicopathologic subtype" https://t.co/TqvSWr4VVL #neuropath