↓ Skip to main content

Conducting a Time Trade-Off Study Alongside a Clinical Trial: A Case Study and Recommendations

Overview of attention for article published in PharmacoEconomics - Open, June 2018
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
12 X users
facebook
1 Facebook page

Citations

dimensions_citation
10 Dimensions

Readers on

mendeley
25 Mendeley
Title
Conducting a Time Trade-Off Study Alongside a Clinical Trial: A Case Study and Recommendations
Published in
PharmacoEconomics - Open, June 2018
DOI 10.1007/s41669-018-0084-1
Pubmed ID
Authors

Jing Shen, Sarah Hill, David Mott, Matthew Breckons, Luke Vale, Rob Pickard

Abstract

Time trade-off (TTO) is an established method in health economics to elicit and value individuals' preferences for different health states. These preferences are expressed in the form of health-state utilities that are typically used to measure health-related quality of life and calculate quality-adjusted life-years in an economic evaluation. The TTO approach to directly elicit health-state utilities is particularly valuable when generic instruments (e.g. EQ-5D) may not fully capture changes in utility in a clinical trial. However, there is limited guidance on how a TTO study should be conducted alongside a clinical trial despite it being a valuable tool. We present an account of the design and development of a TTO study within a clinical trial as a case study. We describe the development of materials needed for the TTO interviews, the piloting of the TTO materials and interview process, and recommendations for future TTO studies. This paper provides a practical guide and reference for future applications of the TTO method alongside a clinical trial.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 24%
Student > Master 3 12%
Student > Bachelor 2 8%
Other 2 8%
Student > Doctoral Student 2 8%
Other 1 4%
Unknown 9 36%
Readers by discipline Count As %
Medicine and Dentistry 7 28%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Business, Management and Accounting 1 4%
Economics, Econometrics and Finance 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 4 16%
Unknown 9 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2019.
All research outputs
#4,076,506
of 23,090,520 outputs
Outputs from PharmacoEconomics - Open
#70
of 333 outputs
Outputs of similar age
#79,332
of 328,710 outputs
Outputs of similar age from PharmacoEconomics - Open
#2
of 7 outputs
Altmetric has tracked 23,090,520 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 333 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,710 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.