↓ Skip to main content

The Glymphatic System: A Beginner’s Guide

Overview of attention for article published in Neurochemical Research, May 2015
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 1,417)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
21 news outlets
blogs
2 blogs
twitter
118 tweeters
facebook
17 Facebook pages
wikipedia
1 Wikipedia page
googleplus
2 Google+ users
video
3 video uploaders

Citations

dimensions_citation
348 Dimensions

Readers on

mendeley
941 Mendeley
citeulike
1 CiteULike
Title
The Glymphatic System: A Beginner’s Guide
Published in
Neurochemical Research, May 2015
DOI 10.1007/s11064-015-1581-6
Pubmed ID
Authors

Nadia Aalling Jessen, Anne Sofie Finmann Munk, Iben Lundgaard, Maiken Nedergaard

Abstract

The glymphatic system is a recently discovered macroscopic waste clearance system that utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote efficient elimination of soluble proteins and metabolites from the central nervous system. Besides waste elimination, the glymphatic system also facilitates  brain-wide distribution of several compounds, including glucose, lipids, amino acids, growth factors, and neuromodulators. Intriguingly, the glymphatic system function mainly during sleep and is largely disengaged during wakefulness. The biological need for sleep across all species may therefore reflect that the brain must enter a state of activity that enables elimination of potentially neurotoxic waste products, including β-amyloid. Since the concept of the glymphatic system is relatively new, we will here review its basic structural elements, organization, regulation, and functions. We will also discuss recent studies indicating that glymphatic function is suppressed in various diseases and that failure of glymphatic function in turn might contribute to pathology in neurodegenerative disorders, traumatic brain injury and stroke.

Twitter Demographics

The data shown below were collected from the profiles of 118 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 941 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 14 1%
United Kingdom 5 <1%
Japan 3 <1%
Spain 2 <1%
Denmark 2 <1%
Norway 1 <1%
Finland 1 <1%
Brazil 1 <1%
Sweden 1 <1%
Other 7 <1%
Unknown 904 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 179 19%
Student > Ph. D. Student 178 19%
Student > Bachelor 151 16%
Student > Master 124 13%
Unspecified 76 8%
Other 232 25%
Unknown 1 <1%
Readers by discipline Count As %
Medicine and Dentistry 234 25%
Neuroscience 213 23%
Agricultural and Biological Sciences 152 16%
Unspecified 123 13%
Biochemistry, Genetics and Molecular Biology 56 6%
Other 162 17%
Unknown 1 <1%

Attention Score in Context

This research output has an Altmetric Attention Score of 271. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2019.
All research outputs
#45,953
of 13,655,409 outputs
Outputs from Neurochemical Research
#1
of 1,417 outputs
Outputs of similar age
#912
of 233,100 outputs
Outputs of similar age from Neurochemical Research
#1
of 32 outputs
Altmetric has tracked 13,655,409 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,417 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 233,100 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.