ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION Application EP-4279588-A3 European Patent Office 17 Jan 2024
CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION Application EP-4234696-A3 European Patent Office 06 Sep 2023
Systems, methods and compositions for sequence manipulation with optimized functional… Grant US-11597919-B2 United States of America 07 Mar 2023
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence… Grant US-11597949-B2 United States of America 07 Mar 2023
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders Grant US-11591581-B2 United States of America 28 Feb 2023
Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9… Grant US-11578312-B2 United States of America 14 Feb 2023
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for… Grant US-11407985-B2 United States of America 09 Aug 2022
COMPOSITION FOR CLEAVING A TARGET DNA COMPRISING A GUIDE RNA SPECIFIC FOR THE TARGET DNA… Grant EP-3733847-B1 European Patent Office 01 Jun 2022
CRISPR-Cas systems, crystal structure and uses thereof Grant US-11155795-B2 United States of America 26 Oct 2021
Delivery, engineering and optimization of systems, methods and compositions for sequence… Grant US-11041173-B2 United States of America 22 Jun 2021
COMPOSITION FOR CLEAVING A TARGET DNA COMPRISING A GUIDE RNA SPECIFIC FOR THE TARGET DNA… Grant EP-3346003-B1 European Patent Office 09 Jun 2021
Delivery, engineering and optimization of tandem guide systems, methods and compositions… Grant US-11008588-B2 United States of America 18 May 2021
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for… Grant US-10946108-B2 United States of America 16 Mar 2021
Methods, models, systems, and apparatus for identifying target sequences for Cas enzymes… Grant US-10930367-B2 United States of America 23 Feb 2021
Crispr enzyme mutations reducing off-target effects Grant US-10876100-B2 United States of America 29 Dec 2020
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders Grant US-10851357-B2 United States of America 01 Dec 2020
Functional genomics using CRISPR-Cas systems, compositions, methods, screens and… Grant US-10781444-B2 United States of America 22 Sep 2020
CRISPR-based genome modification and regulation Grant US-10745716-B2 United States of America 18 Aug 2020
CRISPR-based genome modification and regulation Grant US-10731181-B2 United States of America 04 Aug 2020
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence… Grant US-10711285-B2 United States of America 14 Jul 2020
Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic… Grant US-10577630-B2 United States of America 03 Mar 2020
Systems, methods and compositions for sequence manipulation with optimized functional… Grant US-10550372-B2 United States of America 04 Feb 2020
Crispr enzyme mutations reducing off-target effects Grant US-10494621-B2 United States of America 03 Dec 2019
CRISPR-BASED GENOME MODIFICATION AND REGULATION Grant EP-3363902-B1 European Patent Office 27 Nov 2019
INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF Grant EP-3494997-B1 European Patent Office 18 Sep 2019
CRISPR-Cas component systems, methods and compositions for sequence manipulation Grant US-9840713-B2 United States of America 12 Dec 2017
CRISPR-Cas component systems, methods and compositions for sequence manipulation Grant US-9822372-B2 United States of America 21 Nov 2017