Targeted therapeutic lysosomal enzyme fusion proteins, associated formulations and uses… Grant US-11345904-B2 United States of America 31 May 2022
Methods and compositions for CNS delivery of iduronate-2-sulfatase Grant US-11260112-B2 United States of America 01 Mar 2022
Therapeutic fusion protein comprising an alpha-n-acetylglucosaminidase and a lysosomal… Grant US-11065307-B2 United States of America 20 Jul 2021
Methods and compositions for CNS delivery of heparan n-sulfatase Grant US-11065308-B2 United States of America 20 Jul 2021
Stable formulations for CNS delivery of arylsulfatase A Grant US-10660944-B2 United States of America 26 May 2020
Methods and compositions for CNS delivery of arylsulfatase A Grant US-10646554-B2 United States of America 12 May 2020
Methods of treating Mucopolysaccharidosis IIIB (MPSIIIB) Grant US-10413597-B2 United States of America 17 Sep 2019
Treatment of sanfilippo syndrome type b by intrathecal administration of alpha-n-acetylgluc… Grant US-9814764-B2 United States of America 14 Nov 2017
Methods and compositions for CNS delivery of arylsulfatase A Grant US-9770410-B2 United States of America 26 Sep 2017
Salt forms of (S)-quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate… Grant US-9518049-B2 United States of America 13 Dec 2016
Methods and compositions for CNS delivery of heparan N-sulfatase Grant US-9320711-B2 United States of America 26 Apr 2016
Methods and compositions for CNS delivery of iduronate-2-sulfatase Grant US-9220677-B2 United States of America 29 Dec 2015
Methods and compositions for CNS delivery of iduronate-2-sulfatase Grant US-8545837-B2 United States of America 01 Oct 2013
Combination enzyme replacement and small molecule therapy for treatment of lysosomal… Grant US-8168587-B2 United States of America 01 May 2012
Combination enzyme replacement and small molecule therapy for treatment of lysosomal… Grant US-7910545-B2 United States of America 22 Mar 2011