Title |
Modulation of cellular immunity in medical students
|
---|---|
Published in |
Journal of Behavioral Medicine, February 1986
|
DOI | 10.1007/bf00844640 |
Pubmed ID | |
Authors |
Janice K. Kiecolt-Glaser, Ronald Glaser, Eric C. Strain, Julie C. Stout, Kathleen L. Tarr, Jane E. Holliday, Carl E. Speicher |
Abstract |
This study assessed the psychosocial modulation of cellular immunity in 34 medical-student volunteers. The first blood sample was obtained 1 month before examinations, and the second on the day of examinations. There were significant declines in the percentage of helper/inducer T-lymphocytes, in the helper/inducer-suppressor/cytotoxic-cell ratio, and in natural killer-cell activity in the blood samples obtained on the day of examinations. Half of the subjects were randomly assigned to a relaxation group which met between sample points; the frequency of relaxation practice was a significant predictor of the percentages of helper/inducer cells in the examination sample. Three biochemical nutritional assays (albumin, transferrin, and total iron-binding protein) were within normal limits on both samples. Data from the Brief Symptom Inventory showed significantly increased global self-rated distress associated with examinations in the no-intervention group, compared to nonsignificant change in the relaxation group. Clinical and theoretical implications are discussed. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | <1% |
Unknown | 107 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 16% |
Student > Master | 14 | 13% |
Student > Bachelor | 13 | 12% |
Researcher | 10 | 9% |
Student > Doctoral Student | 7 | 6% |
Other | 19 | 18% |
Unknown | 28 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 32 | 30% |
Medicine and Dentistry | 24 | 22% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Social Sciences | 4 | 4% |
Nursing and Health Professions | 3 | 3% |
Other | 9 | 8% |
Unknown | 32 | 30% |