Title |
Descriptive analysis of sepsis in a developing country
|
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Published in |
International Journal of Emergency Medicine, June 2015
|
DOI | 10.1186/s12245-015-0068-1 |
Pubmed ID | |
Authors |
Gilbert Abou Dagher, Mothana Saadeldine, Rana Bachir, Dina Zebian, Ralphe Bou Chebl |
Abstract |
Most studies on sepsis were conducted in developed countries. The aim of this study is to report on a series of patients with sepsis in a tertiary hospital in a developing country. Patients admitted through the emergency department of a single university-based institution between January 2008 and June 2012, with a final diagnosis of sepsis, bacteremia, or septic shock, were retrieved. A sample of 97 patients was selected. Vital signs at presentation, number of SIRS criteria, use of vasopressors and steroids, and in-hospital mortality were recorded. The mean age was 70.09 ± 16.82, ranging from 19 to 96 years; 48.5 % were females and 51.5 % were males; 42.3 % of the patients were found to be bacteremic. IV fluid requirement during the first 6 h was 1.75 ± 1.96 l. The time for antibiotic initiation was 3.43 ± 4.48 h, with 87.6 % of the antibiotics initiated in the emergency department. Norepinephrine was the most commonly used vasopressor (38.1 %) followed by dopamine (8.2 %), and the inotrope dobutamine (4.1 %); 45.3 % of the patients were admitted to the intensive care unit (ICU), and the remaining 54.7 % were managed on the general practice unit (GPU). A total of 30 (30.9 %) septic patients died. The 28-day mortality was 20.6 %. Deceased patients had greater vasopressor use, a longer stay in the ICU (p = 0.001), and a longer time to norepinephrine use (p = 0.004). This is the first study providing an in-depth analysis of sepsis patients in a developing country, looking at in-hospital mortality, SIRS criteria utility, and at the overall sepsis management. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Peru | 1 | 2% |
Unknown | 58 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 15% |
Other | 8 | 14% |
Student > Bachelor | 7 | 12% |
Researcher | 3 | 5% |
Student > Ph. D. Student | 3 | 5% |
Other | 10 | 17% |
Unknown | 19 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 36% |
Nursing and Health Professions | 4 | 7% |
Unspecified | 2 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Social Sciences | 2 | 3% |
Other | 5 | 8% |
Unknown | 23 | 39% |