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Chemical composition and tyrosinase inhibitory activity of Cinnamomum cassia essential oil

Overview of attention for article published in Botanical Studies, August 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#16 of 188)
  • High Attention Score compared to outputs of the same age (85th percentile)

Mentioned by

news
1 news outlet
wikipedia
4 Wikipedia pages

Citations

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63 Dimensions

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mendeley
104 Mendeley
Title
Chemical composition and tyrosinase inhibitory activity of Cinnamomum cassia essential oil
Published in
Botanical Studies, August 2013
DOI 10.1186/1999-3110-54-10
Pubmed ID
Authors

Chen-Tien Chang, Wen-Lun Chang, Jaw-Cherng Hsu, Ying Shih, Su-Tze Chou

Abstract

Essential oils extracted from aromatic plants exhibit important biological activities and have become increasingly important for scientific research. The essential oil extracted from Cinnamomum cassia Presl (CC-EO) has various functional properties, however, little information is available regarding the tyrosinase inhibitory activity. Therefore, the objectives of this study were to investigate the chemical composition and tyrosinase inhibitory activity of the CC-EO. cis-2-methoxycinnamic acid (43.06%) and cinnamaldehyde (42.37%) were found to be the two major components of the CC-EO identified by gas chromatography-mass spectrometry (GC-MS). The inhibitory activities of CC-EO and its major constituents were further evaluated against mushroom tyrosinase. The results showed that CC-EO and cinnamaldehyde exhibited anti-tyrosinase activities with IC50 values of 6.16 ± 0.04 mg/mL and 4.04 ± 0.08 mg/mL, respectively. However, cis-2-methoxycinnamic acid did not show any anti-tyrosinase activity. The inhibition kinetics were analyzed by Lineweaver-Burk plots and second replots, which revealed that CC-EO and cinnamaldehyde were mixed-type inhibitors. The inhibition constants (Ki) for CC-EO and cinnamaldehyde were calculated to be 4.71 ± 0.09 mg/mL and 2.38 ± 0.09 mg/mL, respectively. These results demonstrate that CC-EO and its major component, cinnamaldehyde, possess potent anti-tyrosinase activities and may be a good source for skin-whitening agents.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Algeria 1 <1%
Unknown 103 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 17%
Student > Master 15 14%
Researcher 11 11%
Student > Ph. D. Student 6 6%
Student > Postgraduate 5 5%
Other 17 16%
Unknown 32 31%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 14%
Chemistry 11 11%
Pharmacology, Toxicology and Pharmaceutical Science 10 10%
Biochemistry, Genetics and Molecular Biology 7 7%
Engineering 5 5%
Other 18 17%
Unknown 38 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2022.
All research outputs
#3,415,510
of 25,374,917 outputs
Outputs from Botanical Studies
#16
of 188 outputs
Outputs of similar age
#28,616
of 210,384 outputs
Outputs of similar age from Botanical Studies
#2
of 4 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 188 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,384 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.