Did you know this? Transdermal buprenorphine (and probably all opioids) worsens depressive symptoms in people advanced dementia. Placebo actually works better! #DrugsDebate #dementia https://t.co/V2G6ITIN1T
RT @Medicinmanden: Vidste du det? "Morfinplastre" med buprenorfin (fx Norspan®) forværrer tilsyneladende depressions-symptomer hos demente…
Vidste du det? "Morfinplastre" med buprenorfin (fx Norspan®) forværrer tilsyneladende depressions-symptomer hos demente. Placebo virker bedre! #sundpol https://t.co/Um2t9HLdMV
RT @AmitAryaMD: 1/ Appreciate this opportunity to discuss! I have often seen patients who would benefit from a palliative care approach in…
1/ Appreciate this opportunity to discuss! I have often seen patients who would benefit from a palliative care approach in #LTC not designated as “palliative care.” A contributing factor may be the myth that #palliativecare is end-of-life care. Early ID
@AmitAryaMD @Tara_Gomes @Mina__T For example, in this study they treated depressed affect in dementia with buprenorphine without much benefit and poor tolerability. https://t.co/fdKTJqzlQn So its about a good assessment of potential pain, and appropriate
“Efficacy and Safety of Analgesic Treatment for Depression in People with Advanced Dementia: Randomised, Multicent…” https://t.co/M5eNA69kSw
Sad to see that the treatment trial failed due to the intolerability of the buprenophine. In retrospect, was depression in dementia the right target/population? https://t.co/cdpDpFlJUC https://t.co/cBzAtWgZdV