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Cancer stem cells: a potential target for cancer therapy

Overview of attention for article published in Cellular & Molecular Life Sciences, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
52 Mendeley
Title
Cancer stem cells: a potential target for cancer therapy
Published in
Cellular & Molecular Life Sciences, May 2015
DOI 10.1007/s00018-015-1920-4
Pubmed ID
Authors

Hong Qiu, Xiaoguang Fang, Qi Luo, Gaoliang Ouyang

Abstract

Current evidence indicates that a subpopulation of cancer cells, named cancer stem cells (CSCs) or tumor-initiating cells, are responsible for the initiation, growth, metastasis, therapy resistance and recurrence of cancers. CSCs share core regulatory pathways with normal stem cells; however, CSCs rely on distinct reprogrammed pathways to maintain stemness and to contribute to the progression of cancers. The specific targeting of CSCs, together with conventional chemotherapy or radiotherapy, may achieve stable remission or cure cancer. Therefore, the identification of CSCs and a better understanding of the complex characteristics of CSCs will provide invaluable diagnostic, therapeutic and prognostic targets for clinical application. In this review, we will introduce the dysregulated properties of CSCs in cancers and discuss the possible challenges in targeting CSCs for cancer treatment.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Luxembourg 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 23%
Student > Master 7 13%
Researcher 6 12%
Unspecified 5 10%
Student > Bachelor 5 10%
Other 17 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 35%
Medicine and Dentistry 10 19%
Agricultural and Biological Sciences 9 17%
Unspecified 8 15%
Chemistry 2 4%
Other 5 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2015.
All research outputs
#1,842,865
of 12,405,771 outputs
Outputs from Cellular & Molecular Life Sciences
#267
of 2,461 outputs
Outputs of similar age
#41,631
of 231,643 outputs
Outputs of similar age from Cellular & Molecular Life Sciences
#6
of 64 outputs
Altmetric has tracked 12,405,771 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,461 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,643 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.