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Cancer stem cells: a potential target for cancer therapy

Overview of attention for article published in Cellular and Molecular Life Sciences, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

blogs
1 blog
twitter
1 X user

Citations

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52 Dimensions

Readers on

mendeley
71 Mendeley
Title
Cancer stem cells: a potential target for cancer therapy
Published in
Cellular and Molecular Life Sciences, May 2015
DOI 10.1007/s00018-015-1920-4
Pubmed ID
Authors

Hong Qiu, Xiaoguang Fang, Qi Luo, Gaoliang Ouyang

Abstract

Current evidence indicates that a subpopulation of cancer cells, named cancer stem cells (CSCs) or tumor-initiating cells, are responsible for the initiation, growth, metastasis, therapy resistance and recurrence of cancers. CSCs share core regulatory pathways with normal stem cells; however, CSCs rely on distinct reprogrammed pathways to maintain stemness and to contribute to the progression of cancers. The specific targeting of CSCs, together with conventional chemotherapy or radiotherapy, may achieve stable remission or cure cancer. Therefore, the identification of CSCs and a better understanding of the complex characteristics of CSCs will provide invaluable diagnostic, therapeutic and prognostic targets for clinical application. In this review, we will introduce the dysregulated properties of CSCs in cancers and discuss the possible challenges in targeting CSCs for cancer treatment.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Luxembourg 1 1%
Unknown 70 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 20%
Researcher 8 11%
Student > Bachelor 8 11%
Student > Master 7 10%
Lecturer 5 7%
Other 18 25%
Unknown 11 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 26 37%
Medicine and Dentistry 11 15%
Agricultural and Biological Sciences 9 13%
Computer Science 2 3%
Engineering 2 3%
Other 6 8%
Unknown 15 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2015.
All research outputs
#4,266,609
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#776
of 4,151 outputs
Outputs of similar age
#52,048
of 265,807 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#11
of 57 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,807 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.