| Title |
Thermally modulated biomolecule transport through nanoconfined channels
|
|---|---|
| Published in |
Discover Nano, April 2015
|
| DOI | 10.1186/s11671-015-0889-0 |
| Pubmed ID | |
| Authors |
Lei Liu, Lizhong Zhu |
| Abstract |
In this work, a nanofluidic device containing both a feed cell and a permeation cell linked by nanopore arrays has been fabricated, which is employed to investigate thermally controlled biomolecular transporting properties through confined nanochannels. The ionic currents modulated by the translocations of goat antibody to human immunoglobulin G (IgG) or bovine serum albumin (BSA) are recorded and analyzed. The results suggest that the modulation effect decreases with the electrolyte concentration increasing, while the effects generated by IgG translocation are more significant than that generated by BSA translocation. More importantly, there is a maximum decreasing value in each modulated current curve with biomolecule concentration increasing for thermally induced intermolecular collision. Furthermore, the turning point for the maximum shifts to lower biomolecule concentrations with the system temperature rising (from 4°C to 45°C), and it is mainly determined by the temperature in the feed cell if the temperature difference exists in the two separated cells. These findings are expected to be valuable for the future design of novel sensing device based on nanopore and/or nanopore arrays. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 8 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 50% |
| Professor > Associate Professor | 1 | 13% |
| Researcher | 1 | 13% |
| Student > Master | 1 | 13% |
| Unknown | 1 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Physics and Astronomy | 2 | 25% |
| Agricultural and Biological Sciences | 2 | 25% |
| Business, Management and Accounting | 1 | 13% |
| Materials Science | 1 | 13% |
| Engineering | 1 | 13% |
| Other | 0 | 0% |
| Unknown | 1 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2015.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Discover Nano
#798
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Outputs of similar age
#240,327
of 279,813 outputs
Outputs of similar age from Discover Nano
#19
of 21 outputs
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