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Primary human nasal epithelial cell response to titanium surface with a nanonetwork structure in nasal implant applications

Overview of attention for article published in Discover Nano, April 2015
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Title
Primary human nasal epithelial cell response to titanium surface with a nanonetwork structure in nasal implant applications
Published in
Discover Nano, April 2015
DOI 10.1186/s11671-015-0849-8
Pubmed ID
Authors

Wei-En Yang, Ming-Ying Lan, Sheng-Wei Lee, Jeng-Kuei Chang, Her-Hsiung Huang

Abstract

In nasal reconstruction applications, the response of cells to titanium (Ti) implants is largely determined by the surface characteristics of the implant. This study investigated an electrochemical anodization surface treatment intended to improve the response of primary human nasal epithelial cells (HNEpC) to Ti surfaces in nasal implant applications. We used a simple and fast electrochemical anodization treatment, i.e., applying anodic current, to produce a titanium dioxide (TiO2) nanonetwork layer on the Ti surface with average lateral pore size below 100 nm, depending on the current applied. The TiO2 nanonetwork layer exhibited enhanced hydrophilicity and protein adsorption ability compared with untreated Ti surfaces. In addition, the spreading morphology, cytoskeletal arrangement, and proliferation of HNEpC on the nanonetwork layer indicated excellent cell response characteristics. This research advances our understanding regarding the means by which a TiO2 nanonetwork layer can improve the response of HNEpC to Ti surfaces in nasal implant applications.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 19%
Unspecified 2 13%
Student > Master 2 13%
Student > Bachelor 1 6%
Other 1 6%
Other 1 6%
Unknown 6 38%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 25%
Biochemistry, Genetics and Molecular Biology 2 13%
Unspecified 1 6%
Social Sciences 1 6%
Chemistry 1 6%
Other 1 6%
Unknown 6 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2015.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Discover Nano
#798
of 1,146 outputs
Outputs of similar age
#241,100
of 279,935 outputs
Outputs of similar age from Discover Nano
#19
of 22 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,146 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,935 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.