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The innate immune response during urinary tract infection and pyelonephritis

Overview of attention for article published in Pediatric Nephrology, June 2013
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Title
The innate immune response during urinary tract infection and pyelonephritis
Published in
Pediatric Nephrology, June 2013
DOI 10.1007/s00467-013-2513-9
Pubmed ID
Authors

John David Spencer, Andrew L. Schwaderer, Brian Becknell, Joshua Watson, David S. Hains

Abstract

Despite its proximity to the fecal flora, the urinary tract is considered sterile. The precise mechanisms by which the urinary tract maintains sterility are not well understood. Host immune responses are critically important in the antimicrobial defense of the urinary tract. During recent years, considerable advances have been made in our understanding of the mechanisms underlying immune homeostasis of the kidney and urinary tract. Dysfunctions in these immune mechanisms may result in acute disease, tissue destruction and overwhelming infection. The objective of this review is to provide an overview of the innate immune response in the urinary tract in response to microbial assault. In doing so, we focus on the role of antimicrobial peptides-a ubiquitous component of the innate immune response.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Germany 1 1%
Unknown 91 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 20%
Researcher 14 15%
Student > Bachelor 12 13%
Unspecified 9 10%
Student > Postgraduate 9 10%
Other 31 33%
Readers by discipline Count As %
Medicine and Dentistry 30 32%
Agricultural and Biological Sciences 17 18%
Biochemistry, Genetics and Molecular Biology 15 16%
Immunology and Microbiology 14 15%
Unspecified 12 13%
Other 6 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2015.
All research outputs
#10,834,852
of 12,222,672 outputs
Outputs from Pediatric Nephrology
#1,715
of 1,916 outputs
Outputs of similar age
#184,751
of 222,426 outputs
Outputs of similar age from Pediatric Nephrology
#37
of 49 outputs
Altmetric has tracked 12,222,672 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,916 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 222,426 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.