Therapeutically active compounds and their methods of use Grant US-11844758-B2 United States of America 19 Dec 2023
Pyruvate kinase activators for use in therapy Grant US-11793806-B2 United States of America 24 Oct 2023
Solid forms of ((s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6… Grant US-11723905-B2 United States of America 15 Aug 2023
Therapeutically active compounds and their methods of use Grant US-11667673-B2 United States of America 06 Jun 2023
Pharmaceutical compositions of therapeutically active compounds Grant US-11504361-B2 United States of America 22 Nov 2022
Therapeutically active compounds and their methods of use Grant US-11505538-B1 United States of America 22 Nov 2022
Treating patients harboring an isocitrate dehydrogenase 1 (IDH-1) mutation Grant US-11497743-B2 United States of America 15 Nov 2022
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-11498913-B2 United States of America 15 Nov 2022
Combination therapy for treating malignancies Grant US-11419859-B2 United States of America 23 Aug 2022
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1) Grant US-11311527-B2 United States of America 26 Apr 2022
Methods of using pyruvate kinase activators Grant US-11234976-B2 United States of America 01 Feb 2022
Therapeutically active compounds and their methods of use Grant US-11021515-B2 United States of America 01 Jun 2021
Treating patients harboring an isocitrate dehydrogenase-1 (IDH-1) mutation Grant US-11013734-B2 United States of America 25 May 2021
Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1) Grant US-11013733-B2 United States of America 25 May 2021
Solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6… Grant US-10959994-B2 United States of America 30 Mar 2021
Therapeutically active compounds and their methods of use Grant US-10946023-B2 United States of America 16 Mar 2021
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma Grant US-10894987-B2 United States of America 19 Jan 2021
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-10889567-B2 United States of America 12 Jan 2021
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma Grant US-10837064-B2 United States of America 17 Nov 2020
Quinolinone five-membered heterocyclic compounds as mutant-isocitrate dehydrogenase… Grant US-10807976-B2 United States of America 20 Oct 2020
Pharmaceutical compositions of therapeutically active compounds Grant US-10799490-B2 United States of America 13 Oct 2020
PROCESS FOR CLASSIFICATION OF GLIOMA Application WO-2020169660-A1 World Intellectual Property Organisation (WIPO) 27 Aug 2020
Therapeutically active compounds and their methods of use Grant US-10717764-B2 United States of America 21 Jul 2020
Methods for diagnosing IDH-mutant cell proliferation disorders Grant US-10711314-B2 United States of America 14 Jul 2020
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma Grant US-10704108-B2 United States of America 07 Jul 2020
Therapeutically active compounds and their methods of use Grant US-10689414-B2 United States of America 23 Jun 2020
Combination therapy for treating malignancies Grant US-10653710-B2 United States of America 19 May 2020
Therapeutically active compositions and their methods of use Grant US-10640534-B2 United States of America 05 May 2020
Pyruvate kinase activators for use in therapy Grant US-10632114-B2 United States of America 28 Apr 2020
Methods and compositions for cell-proliferation-related disorders Grant US-10610125-B2 United States of America 07 Apr 2020
Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-10577329-B2 United States of America 03 Mar 2020
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Application US-10550098-B2 United States of America 04 Feb 2020
Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors Application US-10550099-B2 United States of America 04 Feb 2020
Solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6… Grant US-10532047-B2 United States of America 14 Jan 2020
Pharmaceutical compositions of therapeutically active compounds Grant US-10449184-B2 United States of America 22 Oct 2019
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Application US-10414752-B2 United States of America 17 Sep 2019
Quinolinone five-membered heterocyclic compounds as mutant-isocitrate dehydrogenase… Application US-10407419-B2 United States of America 10 Sep 2019
2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of… Grant US-10376510-B2 United States of America 13 Aug 2019
Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Application US-10294206-B2 United States of America 21 May 2019
Therapeutically active compounds and their methods of use Grant US-10294215-B2 United States of America 21 May 2019
Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors Application US-10280150-B2 United States of America 07 May 2019
Phenyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Application US-10266495-B2 United States of America 23 Apr 2019
Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-10253015-B2 United States of America 09 Apr 2019
7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds and their use as mutant… Application US-10253041-B2 United States of America 09 Apr 2019
Therapeutic compounds and compositions Application US-10202339-B2 United States of America 12 Feb 2019
Oxazolidin-2-one-pyrimidine derivatives and the use thereof as phosphatidylinositol-3-kinas… Application US-10202371-B2 United States of America 12 Feb 2019
Therapeutically active compounds and their methods of use Grant US-10172864-B2 United States of America 08 Jan 2019
1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors Grant US-10137110-B2 United States of America 27 Nov 2018
Benzimidazol-2-amines as MIDH1 inhibitors Application US-10138226-B2 United States of America 27 Nov 2018
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH Application US-10112931-B2 United States of America 30 Oct 2018
Therapeutically active compounds and their methods of use Application US-10105369-B2 United States of America 23 Oct 2018
Therapeutically active compounds and their methods of use Grant US-10017495-B2 United States of America 10 Jul 2018
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-10005734-B2 United States of America 26 Jun 2018
Pyruvate kinase activators for use in therapy Grant US-9980961-B2 United States of America 29 May 2018
Method for treating cell proliferation related disorders Application US-9982309-B2 United States of America 29 May 2018
Pharmaceutical compositions of therapeutically active compounds Grant US-9968595-B2 United States of America 15 May 2018
Therapeutically active compounds and their methods of use Grant US-9889137-B2 United States of America 13 Feb 2018
Therapeutically active compositions and their methods of use Grant US-9856279-B2 United States of America 02 Jan 2018
Therapeutically active compositions and their methods of use Grant US-9850277-B2 United States of America 26 Dec 2017
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-9834539-B2 United States of America 05 Dec 2017
Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors Grant US-9815817-B2 United States of America 14 Nov 2017
Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors Grant US-9771349-B2 United States of America 26 Sep 2017
Therapeutically active compounds and their methods of use Grant US-9732062-B2 United States of America 15 Aug 2017
Therapeutically active compounds and their methods of use Grant US-9694013-B2 United States of America 04 Jul 2017
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH Application US-9688672-B2 United States of America 27 Jun 2017
Phenyl and pyridinyl substituted piperidines and piperazines as inhibitors of IDH1… Grant US-9662327-B2 United States of America 30 May 2017
Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use Grant US-9657004-B2 United States of America 23 May 2017
Therapeutically active compounds and their methods of use Grant US-9579324-B2 United States of America 28 Feb 2017
Means and methods for the determination of (D)-2-hydroxyglutarate (D2HG) or (D)-2-hydroxyad… Grant US-9487815-B2 United States of America 08 Nov 2016
Therapeutically active compositions and their methods of use Application US-9474779-B2 United States of America 25 Oct 2016
Oxazolidin-2-one compounds and uses thereof Application US-9458177-B2 United States of America 04 Oct 2016
Methods and compositions for cell-proliferation-related disorders Application US-9434979-B2 United States of America 06 Sep 2016
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH Grant US-9434719-B2 United States of America 06 Sep 2016
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma Grant US-9353418-B2 United States of America 31 May 2016
METHOD FOR THE DETECTION OF ANTIGEN PRESENTATION Application WO-2016066524-A1 World Intellectual Property Organisation (WIPO) 06 May 2016
Method for the Detection of Antigen Presentation Application EP-3015862-A1 European Patent Office 04 May 2016
Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions… Application US-9296733-B2 United States of America 29 Mar 2016
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH Application US-8957068-B2 United States of America 17 Feb 2015
Method for diagnosing cell proliferation disorders having a neoactive mutation at residue… Application US-8883438-B2 United States of America 11 Nov 2014
Oxazolidin-2-one compounds and uses thereof Application US-8865894-B2 United States of America 21 Oct 2014
Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use Grant US-8742119-B2 United States of America 03 Jun 2014
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma Application US-8685660-B2 United States of America 01 Apr 2014
Methods for the diagnosis and the prognosis of a brain tumor Application US-8367347-B2 United States of America 05 Feb 2013