Title |
5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health
|
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Published in |
Chemistry Central Journal, April 2018
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DOI | 10.1186/s13065-018-0408-3 |
Pubmed ID | |
Authors |
Ummay Mahfuza Shapla, Md. Solayman, Nadia Alam, Md. Ibrahim Khalil, Siew Hua Gan |
Abstract |
An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing sugars in honey and various processed foods in acidic environments when they are heated through the Maillard reaction. In addition to processing, storage conditions affect the formation HMF, and HMF has become a suitable indicator of honey quality. HMF is easily absorbed from food through the gastrointestinal tract and, upon being metabolized into different derivatives, is excreted via urine. In addition to exerting detrimental effects (mutagenic, genotoxic, organotoxic and enzyme inhibitory), HMF, which is converted to a non-excretable, genotoxic compound called 5-sulfoxymethylfurfural, is beneficial to human health by providing antioxidative, anti-allergic, anti-inflammatory, anti-hypoxic, anti-sickling, and anti-hyperuricemic effects. Therefore, HMF is a neo-forming contaminant that draws great attention from scientists. This review compiles updated information regarding HMF formation, detection procedures, mitigation strategies and effects of HMF on honey bees and human health. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 6% |
Turkey | 1 | 3% |
Saudi Arabia | 1 | 3% |
Austria | 1 | 3% |
Japan | 1 | 3% |
Argentina | 1 | 3% |
Unknown | 24 | 77% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 30 | 97% |
Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 775 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 122 | 16% |
Student > Master | 92 | 12% |
Student > Ph. D. Student | 64 | 8% |
Researcher | 32 | 4% |
Student > Doctoral Student | 28 | 4% |
Other | 132 | 17% |
Unknown | 305 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 95 | 12% |
Chemistry | 77 | 10% |
Biochemistry, Genetics and Molecular Biology | 42 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 35 | 5% |
Engineering | 31 | 4% |
Other | 127 | 16% |
Unknown | 368 | 47% |