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Do bioresorbable polyesters have antimicrobial properties?

Overview of attention for article published in Journal of Materials Science: Materials in Medicine, January 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

twitter
2 tweeters
facebook
1 Facebook page

Citations

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2 Dimensions

Readers on

mendeley
17 Mendeley
Title
Do bioresorbable polyesters have antimicrobial properties?
Published in
Journal of Materials Science: Materials in Medicine, January 2018
DOI 10.1007/s10856-017-6021-5
Pubmed ID
Authors

Lukas Gritsch, Christopher Lovell, Wolfgang H. Goldmann, Aldo R. Boccaccini

Abstract

Biodegradable and bioresorbable polyesters (BBPEs) are a widespread class of aliphatic polymers with a plethora of applications in the medical field. Some reports speculate that these polymers have intrinsic antibacterial activity as a consequence of their acidic degradation by-products. The release of organic acids as a result of the hydrolytic degradation of BBPEs in vivo and the resulting pH drop could be an effective inhibitor of the growth of pathogens in the local environment adjacent to BBPE-based devices. However, there is no clear and conclusive evidence in the literature concerning the antibacterial activity of BBPE to support or refute this hypothesis. In this communication we address this point through an assessment of the antibacterial properties of six well-established commercially available BBPEs. Agar diffusion assays and optical density measurements at 600 nm were performed on all the polymer samples to characterize the growth of bacteria and any potential inhibition over an incubation period of 24 h. The results indicated that BBPEs do not possess an intrinsic and immediate antibacterial activity, which is consistent with the clear mismatch between the time-scales for bacterial growth and the rate of degradation of the polyesters.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 47%
Researcher 3 18%
Professor 1 6%
Student > Doctoral Student 1 6%
Unspecified 1 6%
Other 1 6%
Unknown 2 12%
Readers by discipline Count As %
Materials Science 9 53%
Unspecified 2 12%
Immunology and Microbiology 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Chemistry 1 6%
Other 0 0%
Unknown 3 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2019.
All research outputs
#7,227,209
of 13,628,925 outputs
Outputs from Journal of Materials Science: Materials in Medicine
#607
of 857 outputs
Outputs of similar age
#119,949
of 272,059 outputs
Outputs of similar age from Journal of Materials Science: Materials in Medicine
#3
of 14 outputs
Altmetric has tracked 13,628,925 research outputs across all sources so far. This one is in the 46th percentile – i.e., 46% of other outputs scored the same or lower than it.
So far Altmetric has tracked 857 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,059 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.